CRCGN015_HEPG2_48H:E01 Gene Set
Genes
45 genes differentially expressed following the CRCGN015_HEPG2_48H:E01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.10865
|
|
PRKCH
|
protein kinase C, eta
|
4.8674
|
|
TLR4
|
toll-like receptor 4
|
4.527
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
3.9879
|
|
SNX11
|
sorting nexin 11
|
3.84585
|
|
HMOX1
|
heme oxygenase 1
|
3.6586
|
|
TLR8
|
toll-like receptor 8
|
3.34605
|
|
METRN
|
meteorin, glial cell differentiation regulator
|
3.1178
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.79043
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
2.7811
|
|
EVL
|
Enah/Vasp-like
|
2.74645
|
|
PPOX
|
protoporphyrinogen oxidase
|
2.74325
|
|
TLCD3A
|
TLC domain containing 3A
|
2.6153
|
|
MRFAP1L1
|
Morf4 family associated protein 1-like 1
|
2.3407
|
|
KLRB1
|
killer cell lectin-like receptor subfamily B, member 1
|
2.31265
|
|
JCHAIN
|
joining chain of multimeric IgA and IgM
|
2.30505
|
|
AOAH
|
acyloxyacyl hydrolase (neutrophil)
|
2.2774
|
|
FHL2
|
four and a half LIM domains 2
|
2.2672
|
|
GIMAP4
|
GTPase, IMAP family member 4
|
2.221
|
|
RFX5
|
regulatory factor X, 5 (influences HLA class II expression)
|
2.21983
|
|
SQSTM1
|
sequestosome 1
|
2.21175
|
|
OPRPN
|
opiorphin prepropeptide
|
2.1683
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.13965
|
|
GASK1B
|
golgi associated kinase 1B
|
2.1267
|
|
RAB8B
|
RAB8B, member RAS oncogene family
|
2.11905
|
|
MGST3
|
microsomal glutathione S-transferase 3
|
2.1108
|
|
CCR2
|
chemokine (C-C motif) receptor 2
|
2.07045
|
|
AHSP
|
alpha hemoglobin stabilizing protein
|
2.06885
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
2.04605
|
|
CD8A
|
CD8a molecule
|
2.0316
|
|
C3AR1
|
complement component 3a receptor 1
|
2.0057
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PROM1
|
prominin 1
|
-3.80295
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-3.2614
|
|
ANKRD28
|
ankyrin repeat domain 28
|
-2.43245
|
|
SYPL1
|
synaptophysin-like 1
|
-2.29332
|
|
ZBTB35
|
zinc finger and BTB domain containing 35
|
-2.25548
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.2397
|
|
TMEM43
|
transmembrane protein 43
|
-2.2016
|
|
USP6
|
ubiquitin specific peptidase 6
|
-2.15735
|
|
RAP1GDS1
|
RAP1, GTP-GDP dissociation stimulator 1
|
-2.12602
|
|
MBD5
|
methyl-CpG binding domain protein 5
|
-2.11665
|
|
NOTCH2NLB
|
notch 2 N-terminal like B
|
-2.0544
|
|
SSPN
|
sarcospan
|
-2.04278
|
|
SFMBT1
|
Scm-like with four mbt domains 1
|
-2.03655
|
|
INTS6
|
integrator complex subunit 6
|
-2.0116
|
