CRCGN015_HEPG2_48H:E03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tin (ii) chloride 11.11 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_HEPG2_48H:E03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
C2CD2 C2 calcium-dependent domain containing 2 3.69027
BAD BCL2-associated agonist of cell death 3.6596
DENND2D DENN/MADD domain containing 2D 3.63616
EPHB2 EPH receptor B2 3.45325
SNX11 sorting nexin 11 2.99268
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.8604
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.5005
FHL2 four and a half LIM domains 2 2.14536
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.12217

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -2.57983
NAP1L3 nucleosome assembly protein 1-like 3 -2.10814
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -2.00516