CRCGN015_HEPG2_48H:E04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tricresyl phosphate 100.97 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_HEPG2_48H:E04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 4.38617
ZNF586 zinc finger protein 586 4.36957
GRB10 growth factor receptor-bound protein 10 3.3279
FPGS folylpolyglutamate synthase 3.00832
HLA-DRA major histocompatibility complex, class II, DR alpha 2.91666
FSD1 fibronectin type III and SPRY domain containing 1 2.77421
PFKL phosphofructokinase, liver 2.68044
MSRA methionine sulfoxide reductase A 2.50171
GATD3 glutamine amidotransferase class 1 domain containing 3 2.47568
CRTAP cartilage associated protein 2.31495
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.24322
PMM2 phosphomannomutase 2 2.12984
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.11954
DDIT4 DNA-damage-inducible transcript 4 2.11656

decreased expression

Symbol Name Standardized Value
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -3.60359
C2CD5 C2 calcium-dependent domain containing 5 -3.57133
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.18143
KDM3A lysine (K)-specific demethylase 3A -2.56776
S100A3 S100 calcium binding protein A3 -2.11842