CRCGN015_HEPG2_48H:E07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methenamine 100.46 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_HEPG2_48H:E07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 3.81873
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.21785
INTS3 integrator complex subunit 3 3.12753
EPHB2 EPH receptor B2 3.07081
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.48303
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.4506
DENND2D DENN/MADD domain containing 2D 2.0881
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.07039

decreased expression

Symbol Name Standardized Value
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -4.63896
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.96766
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -3.7523
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.20219
ISOC1 isochorismatase domain containing 1 -3.03434
TM9SF3 transmembrane 9 superfamily member 3 -2.89407
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.46682
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.23712
PDLIM1 PDZ and LIM domain 1 -2.14442