CRCGN015_HEPG2_48H:E09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methenamine 11.16 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_HEPG2_48H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKCQ protein kinase C, theta 4.43303
MAP7 microtubule-associated protein 7 3.50553
SPAG4 sperm associated antigen 4 3.435
SNX11 sorting nexin 11 3.25421
ANO10 anoctamin 10 3.02506
EVL Enah/Vasp-like 2.75108
TARP TCR gamma alternate reading frame protein 2.55912
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.48282
CD8A CD8a molecule 2.46312
SCGN secretagogin, EF-hand calcium binding protein 2.29702
DHDDS dehydrodolichyl diphosphate synthase 2.21346
USH1C Usher syndrome 1C (autosomal recessive, severe) 2.21342
ANXA13 annexin A13 2.19239
BMPR1A bone morphogenetic protein receptor, type IA 2.14597
DZIP3 DAZ interacting zinc finger protein 3 2.06035
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.02293
PEX7 peroxisomal biogenesis factor 7 2.01896

decreased expression

Symbol Name Standardized Value
MT1X metallothionein 1X -4.81951
GABARAP GABA(A) receptor-associated protein -2.11854
PDLIM1 PDZ and LIM domain 1 -2.0732
ZNF232 zinc finger protein 232 -2.07018
SARS1 seryl-tRNA synthetase 1 -2.04698
RNF167 ring finger protein 167 -2.00424