CRCGN015_HEPG2_48H:E11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4,4'-methylene-bis(2-methyl?aniline) 33.66 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_HEPG2_48H:E11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 5.10011
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.06378
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.8742
EPN2 epsin 2 3.70875
CHAD chondroadherin 2.40538
GRWD1 glutamate-rich WD repeat containing 1 2.35711
VWA1 von Willebrand factor A domain containing 1 2.28816
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 2.27104
GMPPA GDP-mannose pyrophosphorylase A 2.15263
CERS1 ceramide synthase 1 2.05092

decreased expression

Symbol Name Standardized Value
STAT1 signal transducer and activator of transcription 1, 91kDa -3.88198
JMJD6 jumonji domain containing 6 -3.17694
MT1X metallothionein 1X -2.1918
GBP1 guanylate binding protein 1, interferon-inducible -2.15291
CXCL9 chemokine (C-X-C motif) ligand 9 -2.07256