CRCGN015_HEPG2_48H:E14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bisphenol-a 33.32 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_HEPG2_48H:E14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.44296
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 4.01808
DENND2D DENN/MADD domain containing 2D 3.43208
GATA3 GATA binding protein 3 3.23971
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.02961
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.79254
IGHMBP2 immunoglobulin mu binding protein 2 2.59811
KDM5A lysine (K)-specific demethylase 5A 2.5879
HYOU1 hypoxia up-regulated 1 2.36303
RIC8A RIC8 guanine nucleotide exchange factor A 2.34139
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 2.14561
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.12579
RAB20 RAB20, member RAS oncogene family 2.06709
MERTK MER proto-oncogene, tyrosine kinase 2.06021
OBI1 ORC ubiquitin ligase 1 2.00487

decreased expression

Symbol Name Standardized Value
KIF20A kinesin family member 20A -4.61016
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.0795
BPHL biphenyl hydrolase-like (serine hydrolase) -3.71163
CCNB1 cyclin B1 -3.20046
PDLIM1 PDZ and LIM domain 1 -2.6732
EIF5 eukaryotic translation initiation factor 5 -2.32893
DPYSL2 dihydropyrimidinase-like 2 -2.15219