CRCGN015_HEPG2_48H:E15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bisphenol-a 11.11 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_HEPG2_48H:E15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.32628
SNX11 sorting nexin 11 4.00477
LAGE3 L antigen family, member 3 2.4692
GPR171 G protein-coupled receptor 171 2.37768
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.3444

decreased expression

Symbol Name Standardized Value
CXADR coxsackie virus and adenovirus receptor -7.05893
PRPF4 pre-mRNA processing factor 4 -4.13956
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.75673
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -3.44134
TFRC transferrin receptor -2.92087
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.63895
PDZD2 PDZ domain containing 2 -2.59773
LAPTM4A lysosomal protein transmembrane 4 alpha -2.33871
CSRP2 cysteine and glycine-rich protein 2 -2.23025
FIG4 FIG4 phosphoinositide 5-phosphatase -2.2013
CYB5R2 cytochrome b5 reductase 2 -2.186
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.15889
DPYSL2 dihydropyrimidinase-like 2 -2.13272
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -2.11772
MARK1 MAP/microtubule affinity-regulating kinase 1 -2.10422
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -2.08766
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.02839