CRCGN015_HEPG2_48H:E16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyl gallate 100.46 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

992 genes differentially expressed following the CRCGN015_HEPG2_48H:E16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 7.27789
SPAG4 sperm associated antigen 4 6.42226
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 6.32496
FHL2 four and a half LIM domains 2 5.91249
KDM3A lysine (K)-specific demethylase 3A 5.71951
IER3 immediate early response 3 5.5515
ZFP36 ZFP36 ring finger protein 5.30591
TRIB1 tribbles pseudokinase 1 5.28372
INSIG2 insulin induced gene 2 4.96211
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 4.69564
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.49974
DDIT4 DNA-damage-inducible transcript 4 4.48554
ITGB5 integrin, beta 5 4.47979
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 4.41041
TRIB3 tribbles pseudokinase 3 4.40088
AARS1 alanyl-tRNA synthetase 1 4.36767
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 4.34625
IGFBP3 insulin-like growth factor binding protein 3 4.30557
CDPF1 cysteine-rich, DPF motif domain containing 1 4.21951
FAT1 FAT atypical cadherin 1 4.20551
INPP1 inositol polyphosphate-1-phosphatase 4.18257
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 4.1355
EPS8 epidermal growth factor receptor pathway substrate 8 4.09344
DUSP6 dual specificity phosphatase 6 4.05393
SLC75A1 solute carrier family 75 member 1 4.02626
CHIC2 cysteine-rich hydrophobic domain 2 3.98544
BHLHE40 basic helix-loop-helix family, member e40 3.72873
CASC3 cancer susceptibility candidate 3 3.7249
ANO10 anoctamin 10 3.65887
LRP10 low density lipoprotein receptor-related protein 10 3.63507
RBPJ recombination signal binding protein for immunoglobulin kappa J region 3.627
ZNF862 zinc finger protein 862 3.6048
LOC102724428 serine/threonine-protein kinase SIK1 3.57929
EPHA2 EPH receptor A2 3.56282
ABHD4 abhydrolase domain containing 4 3.55356
ANKZF1 ankyrin repeat and zinc finger domain containing 1 3.53254
MAPK13 mitogen-activated protein kinase 13 3.5054
NPTN neuroplastin 3.49946
ASNS asparagine synthetase (glutamine-hydrolyzing) 3.47202
H2BC21 H2B clustered histone 21 3.44234
GRB10 growth factor receptor-bound protein 10 3.43545
ENO2 enolase 2 (gamma, neuronal) 3.43521
BLCAP bladder cancer associated protein 3.43497
LETMD1 LETM1 domain containing 1 3.40974
GSAP gamma-secretase activating protein 3.37365
SHROOM2 shroom family member 2 3.36911
GBE1 glucan (1,4-alpha-), branching enzyme 1 3.34141
ATF3 activating transcription factor 3 3.34033
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 3.30625
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 3.29238
METTL25B methyltransferase like 25B 3.28988
NPC1 Niemann-Pick disease, type C1 3.28662
TBC1D3G TBC1 domain family member 3G 3.27976
ZMIZ1 zinc finger, MIZ-type containing 1 3.27226
CARS1 cysteinyl-tRNA synthetase 1 3.26722
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.23036
EGR3 early growth response 3 3.22071
TOX3 TOX high mobility group box family member 3 3.20665
SATB1 SATB homeobox 1 3.17579
PFKP phosphofructokinase, platelet 3.17229
SYNGAP1 synaptic Ras GTPase activating protein 1 3.1691
ANGPTL4 angiopoietin-like 4 3.16468
APOD apolipoprotein D 3.15671
IL4R interleukin 4 receptor 3.15052
OXTR oxytocin receptor 3.12445
ZC3H12A zinc finger CCCH-type containing 12A 3.11057
ITFG1 integrin alpha FG-GAP repeat containing 1 3.09322
SARS1 seryl-tRNA synthetase 1 3.09229
NCSTN nicastrin 3.07154
UBL3 ubiquitin-like 3 3.04463
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 3.04268
ARID5A AT rich interactive domain 5A (MRF1-like) 3.04209
LIF leukemia inhibitory factor 3.03911
YEATS2 YEATS domain containing 2 3.03106
ITGA6 integrin, alpha 6 3.01353
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 3.00568
CTSL cathepsin L 2.99648
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.99236
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 2.98566
CLDN4 claudin 4 2.97813
LHFPL2 lipoma HMGIC fusion partner-like 2 2.97299
HILPDA hypoxia inducible lipid droplet-associated 2.96312
LAMP2 lysosomal-associated membrane protein 2 2.95654
STBD1 starch binding domain 1 2.95392
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.94407
DUSP5 dual specificity phosphatase 5 2.94022
TXNRD1 thioredoxin reductase 1 2.93903
HLA-C major histocompatibility complex, class I, C 2.93483
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.92989
PLAT plasminogen activator, tissue 2.91607
ERMP1 endoplasmic reticulum metallopeptidase 1 2.90354
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.90312
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.90089
BLVRA biliverdin reductase A 2.89583
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 2.89037
YARS1 tyrosyl-tRNA synthetase 1 2.88353
ADM adrenomedullin 2.88135
TMEM165 transmembrane protein 165 2.88121
MMP8 matrix metallopeptidase 8 2.86574
NLRP4 NLR family, pyrin domain containing 4 2.86018
GTPBP2 GTP binding protein 2 2.85951
TMEM59 transmembrane protein 59 2.85117
MARCHF3 membrane associated ring-CH-type finger 3 2.83285
SMAD3 SMAD family member 3 2.82732
FAM114A1 family with sequence similarity 114, member A1 2.82617
NFE2L3 nuclear factor, erythroid 2-like 3 2.82568
LGALS8 lectin, galactoside-binding, soluble, 8 2.81723
MANBA mannosidase, beta A, lysosomal 2.81003
TM2D1 TM2 domain containing 1 2.79876
RIOK3 RIO kinase 3 2.79491
TSPAN4 tetraspanin 4 2.79361
SPG11 spastic paraplegia 11 (autosomal recessive) 2.78874
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.78856
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.78526
CST7 cystatin F (leukocystatin) 2.77432
RNF43 ring finger protein 43 2.76466
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 2.75776
DSG2 desmoglein 2 2.75314
QPCT glutaminyl-peptide cyclotransferase 2.75253
GOLGA8A golgin A8 family, member A 2.74644
GADD45B growth arrest and DNA-damage-inducible, beta 2.74627
OSBPL2 oxysterol binding protein-like 2 2.74463
CALCOCO1 calcium binding and coiled-coil domain 1 2.74051
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.73807
CST1 cystatin SN 2.73111
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.7196
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 2.7192
IFRD1 interferon-related developmental regulator 1 2.69839
SUSD6 sushi domain containing 6 2.69796
HBEGF heparin-binding EGF-like growth factor 2.68863
MYH9 myosin, heavy chain 9, non-muscle 2.68536
MED24 mediator complex subunit 24 2.67823
GPR137B G protein-coupled receptor 137B 2.6721
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.66696
GLRX glutaredoxin (thioltransferase) 2.66056
TUBG2 tubulin, gamma 2 2.66038
SQSTM1 sequestosome 1 2.6496
CAMTA2 calmodulin binding transcription activator 2 2.63978
KLHL3 kelch-like family member 3 2.63271
VGLL4 vestigial-like family member 4 2.63228
EDN1 endothelin 1 2.63056
MXI1 MAX interactor 1, dimerization protein 2.62367
EGF epidermal growth factor 2.62265
GAK cyclin G associated kinase 2.61726
RALGDS ral guanine nucleotide dissociation stimulator 2.61409
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.60897
KEAP1 kelch-like ECH-associated protein 1 2.60499
LY96 lymphocyte antigen 96 2.59584
ATF4 activating transcription factor 4 2.59013
CPT1B carnitine palmitoyltransferase 1B (muscle) 2.58992
PKM pyruvate kinase, muscle 2.58091
ZNF34 zinc finger protein 34 2.57846
NR4A1 nuclear receptor subfamily 4, group A, member 1 2.57736
MED15 mediator complex subunit 15 2.57562
CTSH cathepsin H 2.5701
TPCN1 two pore segment channel 1 2.56892
FILIP1L filamin A interacting protein 1-like 2.56817
DRAM1 DNA-damage regulated autophagy modulator 1 2.56704
SLC49A3 solute carrier family 49 member 3 2.55503
SYPL1 synaptophysin-like 1 2.55333
GDI1 GDP dissociation inhibitor 1 2.54655
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 2.54419
TEX14 testis expressed 14 2.54061
RLF rearranged L-myc fusion 2.53466
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 2.52655
DUSP2 dual specificity phosphatase 2 2.51644
PYGB phosphorylase, glycogen; brain 2.51179
SPATA20 spermatogenesis associated 20 2.50602
ARHGAP12 Rho GTPase activating protein 12 2.50433
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 2.49777
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.49427
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.48553
CDIP1 cell death-inducing p53 target 1 2.4825
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.48003
AKTIP AKT interacting protein 2.47636
OLAH oleoyl-ACP hydrolase 2.47513
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 2.47503
PLA2G15 phospholipase A2, group XV 2.47445
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.47436
APMAP adipocyte plasma membrane associated protein 2.47389
MOSPD1 motile sperm domain containing 1 2.46957
TNIP1 TNFAIP3 interacting protein 1 2.46254
EMC3 ER membrane protein complex subunit 3 2.46111
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.46005
VLDLR very low density lipoprotein receptor 2.45792
LOC128125814 uncharacterized LOC128125814 2.45172
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.45114
RNF103 ring finger protein 103 2.44807
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.4374
CEL carboxyl ester lipase 2.4292
SERINC1 serine incorporator 1 2.42827
FRY furry homolog (Drosophila) 2.41858
ZNF750 zinc finger protein 750 2.41239
C5AR1 complement component 5a receptor 1 2.40849
CALML5 calmodulin-like 5 2.40591
MACF1 microtubule-actin crosslinking factor 1 2.39826
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.38938
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.38754
PLBD1 phospholipase B domain containing 1 2.38716
CD40 CD40 molecule, TNF receptor superfamily member 5 2.38502
STX12 syntaxin 12 2.38309
WIPF2 WAS/WASL interacting protein family, member 2 2.38192
CYTH4 cytohesin 4 2.3747
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 2.3697
DNMBP dynamin binding protein 2.36969
ORAI3 ORAI calcium release-activated calcium modulator 3 2.36827
TSC1 tuberous sclerosis 1 2.36171
ITPKC inositol-trisphosphate 3-kinase C 2.35871
TMEM45A transmembrane protein 45A 2.35633
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.35024
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.3499
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 2.34511
MAP3K8 mitogen-activated protein kinase kinase kinase 8 2.34319
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 2.34024
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.33957
PPARD peroxisome proliferator-activated receptor delta 2.33685
ALAS1 5'-aminolevulinate synthase 1 2.33461
CRYGB crystallin, gamma B 2.33405
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 2.33062
STC1 stanniocalcin 1 2.32903
GARS1 glycyl-tRNA synthetase 1 2.32817
TM2D3 TM2 domain containing 3 2.32214
NOP53 NOP53 ribosome biogenesis factor 2.31972
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.31771
MYOD1 myogenic differentiation 1 2.31643
FOXI1 forkhead box I1 2.31581
ZNF274 zinc finger protein 274 2.31223
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 2.30706
PLK3 polo-like kinase 3 2.30407
PSG2 pregnancy specific beta-1-glycoprotein 2 2.29893
MAST4 microtubule associated serine/threonine kinase family member 4 2.29542
GRAMD2B GRAM domain containing 2B 2.29213
NPPA natriuretic peptide A 2.2919
NR4A2 nuclear receptor subfamily 4, group A, member 2 2.28949
ATP11B ATPase, class VI, type 11B 2.28499
STAP2 signal transducing adaptor family member 2 2.28479
MTMR14 myotubularin related protein 14 2.27805
TMEM50A transmembrane protein 50A 2.27213
DENND4B DENN/MADD domain containing 4B 2.26914
ANKRD28 ankyrin repeat domain 28 2.26245
IER5 immediate early response 5 2.26024
NT5E 5'-nucleotidase, ecto (CD73) 2.25986
CLSTN3 calsyntenin 3 2.25894
EGLN3 egl-9 family hypoxia-inducible factor 3 2.2551
RTN3 reticulon 3 2.24891
WBP2 WW domain binding protein 2 2.2481
ZNF133 zinc finger protein 133 2.24684
DDB2 damage-specific DNA binding protein 2, 48kDa 2.2437
CASS4 Cas scaffolding protein family member 4 2.23813
MORC3 MORC family CW-type zinc finger 3 2.23736
CLIP3 CAP-GLY domain containing linker protein 3 2.23366
MBNL2 muscleblind-like splicing regulator 2 2.23325
NDRG1 N-myc downstream regulated 1 2.22997
CBX4 chromobox homolog 4 2.22874
KLF4 Kruppel-like factor 4 (gut) 2.22612
DUSP8 dual specificity phosphatase 8 2.22601
SCPEP1 serine carboxypeptidase 1 2.22434
EMC7 ER membrane protein complex subunit 7 2.22424
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 2.22232
HEBP1 heme binding protein 1 2.21726
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.21273
VEGFC vascular endothelial growth factor C 2.21028
LARP6 La ribonucleoprotein domain family, member 6 2.20939
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 2.20801
ADGRG1 adhesion G protein-coupled receptor G1 2.20549
MAN2B2 mannosidase, alpha, class 2B, member 2 2.20239
ZCWPW1 zinc finger, CW type with PWWP domain 1 2.20008
FSHB follicle stimulating hormone, beta polypeptide 2.1993
ULK1 unc-51 like autophagy activating kinase 1 2.19823
USP3 ubiquitin specific peptidase 3 2.19211
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 2.18972
COL9A2 collagen, type IX, alpha 2 2.18898
HPSE2 heparanase 2 (inactive) 2.18823
TUFT1 tuftelin 1 2.18396
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.18189
FOSL1 FOS-like antigen 1 2.18099
EGR1 early growth response 1 2.17911
SRPK3 SRSF protein kinase 3 2.17885
HCK HCK proto-oncogene, Src family tyrosine kinase 2.17696
IRF2 interferon regulatory factor 2 2.1748
YPEL5 yippee-like 5 (Drosophila) 2.17371
RGS16 regulator of G-protein signaling 16 2.17212
HLA-A major histocompatibility complex, class I, A 2.17159
NFIL3 nuclear factor, interleukin 3 regulated 2.17115
ACSL5 acyl-CoA synthetase long-chain family member 5 2.1678
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.16744
IL10 interleukin 10 2.1661
NFE2L1 nuclear factor, erythroid 2-like 1 2.16506
SMAD7 SMAD family member 7 2.16427
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 2.1621
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.162
UPK1A uroplakin 1A 2.15613
FMO5 flavin containing monooxygenase 5 2.15602
POF1B premature ovarian failure, 1B 2.15231
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.15087
TMEM184B transmembrane protein 184B 2.1458
TMEM132A transmembrane protein 132A 2.14444
IGF2R insulin-like growth factor 2 receptor 2.14327
IQSEC1 IQ motif and Sec7 domain 1 2.14029
CCPG1 cell cycle progression 1 2.13894
PTPRM protein tyrosine phosphatase, receptor type, M 2.13769
LRRN2 leucine rich repeat neuronal 2 2.13601
APOL1 apolipoprotein L, 1 2.13211
RAP1GAP RAP1 GTPase activating protein 2.12585
MAN1B1 mannosidase, alpha, class 1B, member 1 2.12576
KLF9 Kruppel-like factor 9 2.12371
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.11518
CARD9 caspase recruitment domain family, member 9 2.11196
EIF4A2 eukaryotic translation initiation factor 4A2 2.10945
SH3BP4 SH3-domain binding protein 4 2.10686
PFKM phosphofructokinase, muscle 2.10433
RNF111 ring finger protein 111 2.10209
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.10193
BEST1 bestrophin 1 2.1014
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.09934
RNF13 ring finger protein 13 2.09609
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 2.09593
MYO18A myosin XVIIIA 2.09099
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.08921
MAGEA8 melanoma antigen family A8 2.08828
ZNF337 zinc finger protein 337 2.08713
KIAA0232 KIAA0232 2.08707
TGM3 transglutaminase 3 2.08576
SLC26A6 solute carrier family 26 (anion exchanger), member 6 2.0785
LRRC31 leucine rich repeat containing 31 2.07808
ISG20 interferon stimulated exonuclease gene 20kDa 2.07219
MYOG myogenin (myogenic factor 4) 2.07136
IGFBP1 insulin-like growth factor binding protein 1 2.06459
SLC67A1 solute carrier family 67 member 1 2.06352
PHF21A PHD finger protein 21A 2.06315
IL26 interleukin 26 2.06269
ZNF516 zinc finger protein 516 2.06163
BCL2L2 BCL2-like 2 2.06139
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 2.05863
TRPV2 transient receptor potential cation channel, subfamily V, member 2 2.05719
PHKB phosphorylase kinase, beta 2.0559
FNDC3B fibronectin type III domain containing 3B 2.05315
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.05111
PERP PERP, TP53 apoptosis effector 2.05007
FLNC filamin C, gamma 2.04996
HLA-B major histocompatibility complex, class I, B 2.04933
LAD1 ladinin 1 2.04898
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.04781
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 2.0473
LOC102723713 TP53-target gene 3 protein 2.04647
RAB7A RAB7A, member RAS oncogene family 2.04531
FGF9 fibroblast growth factor 9 2.04518
ITGAV integrin, alpha V 2.04228
SNAI1 snail family zinc finger 1 2.04059
PXDC1 PX domain containing 1 2.03867
CD59 CD59 molecule, complement regulatory protein 2.03741
CD200 CD200 molecule 2.03643
TRPC1 transient receptor potential cation channel, subfamily C, member 1 2.0339
POMT1 protein-O-mannosyltransferase 1 2.0311
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.02999
CLIP1 CAP-GLY domain containing linker protein 1 2.02929
FMNL3 formin-like 3 2.0287
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.02725
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 2.02645
CLTB clathrin, light chain B 2.02549
UCN urocortin 2.02065
PADI4 peptidyl arginine deiminase, type IV 2.02003
POLI polymerase (DNA directed) iota 2.01862
MARS1 methionyl-tRNA synthetase 1 2.0167
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.01668
XPC xeroderma pigmentosum, complementation group C 2.01663
RPH3AL rabphilin 3A-like (without C2 domains) 2.01607
CTBS chitobiase, di-N-acetyl- 2.01558
CLCNKA chloride channel, voltage-sensitive Ka 2.01554
CCNG2 cyclin G2 2.01353
ARHGAP5 Rho GTPase activating protein 5 2.01223
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 2.01215
TNIP2 TNFAIP3 interacting protein 2 2.01059
PRSS53 protease, serine, 53 2.00675
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 2.006
ATXN1 ataxin 1 2.00219
AHCYL1 adenosylhomocysteinase-like 1 2.00174
GBP2 guanylate binding protein 2, interferon-inducible 2.00159
TMEM74B transmembrane protein 74B 2.00057
CLEC5A C-type lectin domain family 5, member A 2.00007

decreased expression

Symbol Name Standardized Value
IL17RB interleukin 17 receptor B -5.79691
CDC20 cell division cycle 20 -5.69187
PLK1 polo-like kinase 1 -5.41863
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -5.02655
HEATR1 HEAT repeat containing 1 -4.90575
CCNB1 cyclin B1 -4.85117
CIAPIN1 cytokine induced apoptosis inhibitor 1 -4.74365
BIRC5 baculoviral IAP repeat containing 5 -4.68957
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -4.59813
OIP5 Opa interacting protein 5 -4.59395
LBR lamin B receptor -4.55919
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.53932
CCNA2 cyclin A2 -4.47076
PAK1IP1 PAK1 interacting protein 1 -4.40912
RFC2 replication factor C (activator 1) 2, 40kDa -4.32906
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -4.23855
NUP93 nucleoporin 93kDa -4.15434
MCM10 minichromosome maintenance complex component 10 -4.13217
HAT1 histone acetyltransferase 1 -4.12985
DEPDC1 DEP domain containing 1 -4.11949
STMN1 stathmin 1 -4.07872
MCM3 minichromosome maintenance complex component 3 -4.07378
AURKB aurora kinase B -4.04314
KIF20A kinesin family member 20A -4.0149
EXO1 exonuclease 1 -4.00609
NUP85 nucleoporin 85kDa -3.9986
MTFR1 mitochondrial fission regulator 1 -3.98034
NEK2 NIMA-related kinase 2 -3.97721
CCNB2 cyclin B2 -3.93918
ERCC6L excision repair cross-complementation group 6-like -3.90047
SPC25 SPC25, NDC80 kinetochore complex component -3.87116
TDP1 tyrosyl-DNA phosphodiesterase 1 -3.83335
HADH hydroxyacyl-CoA dehydrogenase -3.82781
SHMT1 serine hydroxymethyltransferase 1 (soluble) -3.78997
LMNB1 lamin B1 -3.78679
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.77363
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -3.74172
KIF18A kinesin family member 18A -3.72237
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.71854
UBE2C ubiquitin-conjugating enzyme E2C -3.67191
LCMT2 leucine carboxyl methyltransferase 2 -3.66297
SPAG5 sperm associated antigen 5 -3.64901
PIMREG PICALM interacting mitotic regulator -3.63756
HMGN2 high mobility group nucleosomal binding domain 2 -3.63726
NOLC1 nucleolar and coiled-body phosphoprotein 1 -3.63349
TBCE tubulin folding cofactor E -3.61614
CENPA centromere protein A -3.61064
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -3.60255
GMPPB GDP-mannose pyrophosphorylase B -3.599
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.59695
TPX2 TPX2, microtubule-associated -3.59175
BORA bora, aurora kinase A activator -3.5879
EXOSC9 exosome component 9 -3.57644
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.57321
TRMT5 tRNA methyltransferase 5 -3.57181
CDCA3 cell division cycle associated 3 -3.56335
TMPO thymopoietin -3.55726
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.5509
TIPIN TIMELESS interacting protein -3.51396
RFC3 replication factor C (activator 1) 3, 38kDa -3.50924
CASP3 caspase 3, apoptosis-related cysteine peptidase -3.49993
ELOVL6 ELOVL fatty acid elongase 6 -3.49332
CENPN centromere protein N -3.48492
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.48278
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.47923
DCTPP1 dCTP pyrophosphatase 1 -3.46985
CENPS-CORT CENPS-CORT readthrough -3.45947
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.4579
SDF2L1 stromal cell-derived factor 2-like 1 -3.43561
FEN1 flap structure-specific endonuclease 1 -3.42829
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -3.41827
DHFR dihydrofolate reductase -3.39644
EBNA1BP2 EBNA1 binding protein 2 -3.38786
PARP1 poly (ADP-ribose) polymerase 1 -3.37805
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -3.35968
MFAP4 microfibrillar-associated protein 4 -3.35511
PFAS phosphoribosylformylglycinamidine synthase -3.35448
CDK4 cyclin-dependent kinase 4 -3.34569
KIF4A kinesin family member 4A -3.33843
RPA3 replication protein A3, 14kDa -3.33754
CENPE centromere protein E, 312kDa -3.32928
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.32285
OSBPL11 oxysterol binding protein-like 11 -3.31642
H2AZ2 H2A.Z variant histone 2 -3.30116
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.2999
DBF4 DBF4 zinc finger -3.29682
KIF11 kinesin family member 11 -3.29662
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.29176
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.2914
VAV3 vav 3 guanine nucleotide exchange factor -3.2851
SOAT2 sterol O-acyltransferase 2 -3.28492
RIOX1 ribosomal oxygenase 1 -3.27411
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -3.27362
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -3.26789
MCM6 minichromosome maintenance complex component 6 -3.26462
COQ3 coenzyme Q3 methyltransferase -3.25929
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -3.23601
THAP11 THAP domain containing 11 -3.23566
RUVBL1 RuvB-like AAA ATPase 1 -3.2219
KIF22 kinesin family member 22 -3.2187
TMEM100 transmembrane protein 100 -3.21533
KIF14 kinesin family member 14 -3.21118
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.20964
RFWD3 ring finger and WD repeat domain 3 -3.20314
GCSH glycine cleavage system protein H (aminomethyl carrier) -3.20235
PLPBP pyridoxal phosphate binding protein -3.20058
USP1 ubiquitin specific peptidase 1 -3.1886
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -3.18095
SKA1 spindle and kinetochore associated complex subunit 1 -3.16622
WDR76 WD repeat domain 76 -3.16207
TTC27 tetratricopeptide repeat domain 27 -3.15735
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.15575
PRPF4 pre-mRNA processing factor 4 -3.13512
SHCBP1 SHC SH2-domain binding protein 1 -3.13445
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.12801
TRIP13 thyroid hormone receptor interactor 13 -3.12378
MIS18A MIS18 kinetochore protein A -3.12058
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -3.11089
ASF1B anti-silencing function 1B histone chaperone -3.10407
MCM4 minichromosome maintenance complex component 4 -3.09924
C5 complement component 5 -3.09271
ENOPH1 enolase-phosphatase 1 -3.08528
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -3.08487
FXN frataxin -3.07699
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -3.07497
NANS N-acetylneuraminic acid synthase -3.07168
GINS4 GINS complex subunit 4 (Sld5 homolog) -3.06737
SNX4 sorting nexin 4 -3.05309
PUS3 pseudouridylate synthase 3 -3.05023
UXT ubiquitously-expressed, prefoldin-like chaperone -3.04124
CDCA8 cell division cycle associated 8 -3.03473
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.02714
NCAPD3 non-SMC condensin II complex, subunit D3 -3.0219
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -3.02119
DHCR24 24-dehydrocholesterol reductase -3.02023
UFM1 ubiquitin-fold modifier 1 -3.00358
MRPL11 mitochondrial ribosomal protein L11 -2.99748
MRPL3 mitochondrial ribosomal protein L3 -2.9967
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.99367
KIFC1 kinesin family member C1 -2.98534
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.98195
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.98189
ECD ecdysoneless homolog (Drosophila) -2.98169
MCM7 minichromosome maintenance complex component 7 -2.97343
KNOP1 lysine-rich nucleolar protein 1 -2.96614
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.96397
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.95752
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.94502
SRSF3 serine/arginine-rich splicing factor 3 -2.94385
SPOUT1 SPOUT domain containing methyltransferase 1 -2.94359
DHODH dihydroorotate dehydrogenase (quinone) -2.93662
APOO apolipoprotein O -2.93506
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.93463
RPAIN RPA interacting protein -2.92618
TMEM97 transmembrane protein 97 -2.92544
PDF peptide deformylase (mitochondrial) -2.92479
TXNDC9 thioredoxin domain containing 9 -2.91456
NUTF2 nuclear transport factor 2 -2.89791
NUSAP1 nucleolar and spindle associated protein 1 -2.89184
HJURP Holliday junction recognition protein -2.88872
KIF23 kinesin family member 23 -2.87809
ADI1 acireductone dioxygenase 1 -2.87523
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.87364
PALB2 partner and localizer of BRCA2 -2.87095
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.85934
RFXAP regulatory factor X-associated protein -2.85772
NUP62 nucleoporin 62kDa -2.85692
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -2.85124
MSTO1 misato 1, mitochondrial distribution and morphology regulator -2.84865
MRPL19 mitochondrial ribosomal protein L19 -2.84523
MCM9 minichromosome maintenance complex component 9 -2.84346
TFDP1 transcription factor Dp-1 -2.84015
RACGAP1 Rac GTPase activating protein 1 -2.83542
BRCA1 breast cancer 1, early onset -2.8308
ETNK2 ethanolamine kinase 2 -2.82955
LBHD1 LBH domain containing 1 -2.82498
SRSF2 serine/arginine-rich splicing factor 2 -2.82133
CRLF3 cytokine receptor-like factor 3 -2.82043
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 -2.81895
PTMA prothymosin, alpha -2.81168
XPO7 exportin 7 -2.81067
CACYBP calcyclin binding protein -2.80955
NPY1R neuropeptide Y receptor Y1 -2.78517
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.78031
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.77464
CISD1 CDGSH iron sulfur domain 1 -2.7707
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.7694
WRAP53 WD repeat containing, antisense to TP53 -2.76921
FBXO5 F-box protein 5 -2.76896
ISOC2 isochorismatase domain containing 2 -2.7667
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.76658
PECR peroxisomal trans-2-enoyl-CoA reductase -2.76646
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.7646
NUDC nudC nuclear distribution protein -2.76263
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.75971
PREB prolactin regulatory element binding -2.75491
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.74977
CENPI centromere protein I -2.74823
TFAM transcription factor A, mitochondrial -2.74331
PYCR3 pyrroline-5-carboxylate reductase 3 -2.74112
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.73433
UNG uracil-DNA glycosylase -2.73246
CDC73 cell division cycle 73 -2.73093
FANCC Fanconi anemia, complementation group C -2.72333
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.71888
ZWILCH zwilch kinetochore protein -2.71705
PBK PDZ binding kinase -2.71696
DCTN5 dynactin 5 (p25) -2.71182
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -2.7118
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.70985
CETN2 centrin, EF-hand protein, 2 -2.70974
PHKG2 phosphorylase kinase, gamma 2 (testis) -2.70919
GPR20 G protein-coupled receptor 20 -2.70687
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -2.70595
CDC6 cell division cycle 6 -2.70506
GEMIN6 gem (nuclear organelle) associated protein 6 -2.701
PNPLA3 patatin-like phospholipase domain containing 3 -2.7002
MCM5 minichromosome maintenance complex component 5 -2.69731
HGH1 HGH1 homolog (S. cerevisiae) -2.69674
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.69607
RWDD3 RWD domain containing 3 -2.69363
CDK2 cyclin-dependent kinase 2 -2.69181
PNPO pyridoxamine 5'-phosphate oxidase -2.67692
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.67434
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.67191
MYL9 myosin, light chain 9, regulatory -2.66654
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -2.66497
NFYB nuclear transcription factor Y, beta -2.66479
CDKN3 cyclin-dependent kinase inhibitor 3 -2.66254
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.66172
TBC1D10C TBC1 domain family, member 10C -2.66046
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.65795
HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine -2.65538
RRP1B ribosomal RNA processing 1B -2.65354
TOP2A topoisomerase (DNA) II alpha 170kDa -2.65037
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.64776
CDC25C cell division cycle 25C -2.64652
BOP1 block of proliferation 1 -2.64602
FANCG Fanconi anemia, complementation group G -2.64342
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.63992
EXOSC8 exosome component 8 -2.62816
RIDA reactive intermediate imine deaminase A homolog -2.62746
NCAPH non-SMC condensin I complex, subunit H -2.62742
SH3D19 SH3 domain containing 19 -2.62607
PARPBP PARP1 binding protein -2.62236
EXOSC2 exosome component 2 -2.62081
GDAP1 ganglioside induced differentiation associated protein 1 -2.62066
HMGB1 high mobility group box 1 -2.61937
CCNF cyclin F -2.61861
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -2.61817
RRM1 ribonucleotide reductase M1 -2.61811
RCC1 regulator of chromosome condensation 1 -2.61645
DGKH diacylglycerol kinase, eta -2.60963
LYRM2 LYR motif containing 2 -2.60843
TTK TTK protein kinase -2.60232
IDE insulin-degrading enzyme -2.60038
PM20D1 peptidase M20 domain containing 1 -2.60021
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.59953
MKI67 marker of proliferation Ki-67 -2.5994
TCP1 t-complex 1 -2.59837
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.58418
WDR43 WD repeat domain 43 -2.58253
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.58094
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.578
TCOF1 Treacher Collins-Franceschetti syndrome 1 -2.57128
NCAPG2 non-SMC condensin II complex, subunit G2 -2.56211
CDCA4 cell division cycle associated 4 -2.56201
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.556
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.55534
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.55171
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.54616
POMK protein-O-mannose kinase -2.54568
ZNF696 zinc finger protein 696 -2.54424
BAG4 BCL2-associated athanogene 4 -2.54243
HOXA7 homeobox A7 -2.54163
MCUR1 mitochondrial calcium uniporter regulator 1 -2.53892
NUP160 nucleoporin 160kDa -2.53601
MTPAP mitochondrial poly(A) polymerase -2.53396
DTD1 D-tyrosyl-tRNA deacylase 1 -2.53159
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.52815
GSDMD gasdermin D -2.52777
PNO1 partner of NOB1 homolog (S. cerevisiae) -2.52705
MYLK myosin light chain kinase -2.52352
DCPH1 damage control phosphatase 1 -2.52205
RABEPK Rab9 effector protein with kelch motifs -2.52175
EI24 etoposide induced 2.4 -2.52067
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.52045
APOH apolipoprotein H (beta-2-glycoprotein I) -2.51979
CHEK1 checkpoint kinase 1 -2.51476
RPN1 ribophorin I -2.51396
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.51375
JADE3 jade family PHD finger 3 -2.51205
PTBP1 polypyrimidine tract binding protein 1 -2.51116
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.50891
RPP38 ribonuclease P/MRP 38kDa subunit -2.50634
DCXR dicarbonyl/L-xylulose reductase -2.50163
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -2.50021
LYRM1 LYR motif containing 1 -2.49697
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.49602
HMGA2 high mobility group AT-hook 2 -2.49586
PDE3B phosphodiesterase 3B, cGMP-inhibited -2.49574
MRPL39 mitochondrial ribosomal protein L39 -2.49106
PLK4 polo-like kinase 4 -2.48674
HMGN1 high mobility group nucleosome binding domain 1 -2.48557
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.48463
HSPA8 heat shock 70kDa protein 8 -2.48406
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.482
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.47242
METTL9 methyltransferase like 9 -2.46805
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.46516
LIPT1 lipoyltransferase 1 -2.46323
WRN Werner syndrome, RecQ helicase-like -2.45569
TBCCD1 TBCC domain containing 1 -2.45489
CUTC cutC copper transporter -2.45336
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -2.4511
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.44731
CEP55 centrosomal protein 55kDa -2.43961
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.43467
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.43212
RAD51D RAD51 paralog D -2.42623
NLE1 notchless homolog 1 (Drosophila) -2.42443
KIF15 kinesin family member 15 -2.42428
ANAPC15 anaphase promoting complex subunit 15 -2.42273
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.4216
PSRC1 proline/serine-rich coiled-coil 1 -2.41998
MTG1 mitochondrial ribosome-associated GTPase 1 -2.41926
ODF2 outer dense fiber of sperm tails 2 -2.40913
NDC1 NDC1 transmembrane nucleoporin -2.40893
VRK1 vaccinia related kinase 1 -2.40609
GTSE1 G-2 and S-phase expressed 1 -2.40582
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 -2.4031
ISOC1 isochorismatase domain containing 1 -2.39823
DPT dermatopontin -2.39316
ERH enhancer of rudimentary homolog (Drosophila) -2.39121
LDHD lactate dehydrogenase D -2.38451
TTF1 transcription termination factor, RNA polymerase I -2.38372
RIOK2 RIO kinase 2 -2.38005
SETD6 SET domain containing 6 -2.37887
ASPN asporin -2.37571
ADISSP adipose secreted signaling protein -2.37272
MAT2A methionine adenosyltransferase II, alpha -2.36941
TWNK twinkle mtDNA helicase -2.36745
RPP30 ribonuclease P/MRP 30kDa subunit -2.3621
TMEM11 transmembrane protein 11 -2.36209
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.35739
SSRP1 structure specific recognition protein 1 -2.3558
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.35243
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.35222
ASTE1 asteroid homolog 1 (Drosophila) -2.35048
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.34951
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -2.3466
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.34558
FADD Fas (TNFRSF6)-associated via death domain -2.34465
CKAP2 cytoskeleton associated protein 2 -2.34409
BRMS1L breast cancer metastasis-suppressor 1-like -2.34257
RUVBL2 RuvB-like AAA ATPase 2 -2.34108
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.33989
GEMIN2 gem (nuclear organelle) associated protein 2 -2.33959
ST20-MTHFS ST20-MTHFS readthrough -2.33953
GPX4 glutathione peroxidase 4 -2.33778
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -2.33587
MRPL58 mitochondrial ribosomal protein L58 -2.33501
VAT1 vesicle amine transport 1 -2.33314
DLAT dihydrolipoamide S-acetyltransferase -2.332
BRIX1 BRX1, biogenesis of ribosomes -2.33103
PEX26 peroxisomal biogenesis factor 26 -2.32867
WDR46 WD repeat domain 46 -2.32726
TTC26 tetratricopeptide repeat domain 26 -2.32717
NOP56 NOP56 ribonucleoprotein -2.32621
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.32543
CAMKMT calmodulin-lysine N-methyltransferase -2.32496
DSN1 DSN1, MIS12 kinetochore complex component -2.32274
MRPS7 mitochondrial ribosomal protein S7 -2.32241
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.3221
NLRP2B NLR family pyrin domain containing 2B -2.32044
WDCP WD repeat and coiled coil containing -2.3203
PSMC3IP PSMC3 interacting protein -2.31827
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.31729
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -2.3167
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.31667
CALM1 calmodulin 1 (phosphorylase kinase, delta) -2.31583
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.31487
ZMYM1 zinc finger, MYM-type 1 -2.31417
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.31386
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.31354
PYDC1 PYD (pyrin domain) containing 1 -2.30558
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -2.30536
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.30527
PALS2 protein associated with LIN7 2, MAGUK p55 family member -2.30469
LDLR low density lipoprotein receptor -2.30294
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -2.30127
ERI2 ERI1 exoribonuclease family member 2 -2.29902
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.29833
TOE1 target of EGR1, member 1 (nuclear) -2.29662
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -2.29555
CFAP298 cilia and flagella associated protein 298 -2.29326
SNCAIP synuclein, alpha interacting protein -2.29132
SRSF1 serine/arginine-rich splicing factor 1 -2.29127
CHL1 cell adhesion molecule L1-like -2.28901
MTCH2 mitochondrial carrier 2 -2.28875
SMC3 structural maintenance of chromosomes 3 -2.28273
F9 coagulation factor IX -2.2827
POLR1G RNA polymerase I subunit G -2.2815
GFOD1 glucose-fructose oxidoreductase domain containing 1 -2.28125
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.2803
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.27595
NPM3 nucleophosmin/nucleoplasmin 3 -2.27563
ORC6 origin recognition complex, subunit 6 -2.27502
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.2741
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.27405
MED7 mediator complex subunit 7 -2.27046
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.27
COA7 cytochrome c oxidase assembly factor 7 (putative) -2.2692
LZTFL1 leucine zipper transcription factor-like 1 -2.26902
UROS uroporphyrinogen III synthase -2.2689
CSRP2 cysteine and glycine-rich protein 2 -2.26867
NDNF neuron-derived neurotrophic factor -2.26692
GATD3 glutamine amidotransferase class 1 domain containing 3 -2.26606
LY86 lymphocyte antigen 86 -2.26309
MSMO1 methylsterol monooxygenase 1 -2.26223
THUMPD1 THUMP domain containing 1 -2.26178
NRIP3 nuclear receptor interacting protein 3 -2.26153
NPAT nuclear protein, ataxia-telangiectasia locus -2.26019
MGMT O-6-methylguanine-DNA methyltransferase -2.25929
APEH acylaminoacyl-peptide hydrolase -2.25618
NPY neuropeptide Y -2.25522
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.25341
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.25114
HMBS hydroxymethylbilane synthase -2.25018
SNRPF small nuclear ribonucleoprotein polypeptide F -2.24477
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.24426
HNRNPK heterogeneous nuclear ribonucleoprotein K -2.24322
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.24306
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -2.23623
HOXA5 homeobox A5 -2.23369
SRRD SRR1 domain containing -2.2307
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -2.23059
ASRGL1 asparaginase like 1 -2.23036
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.23032
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -2.23008
AGMAT agmatine ureohydrolase (agmatinase) -2.22848
SFXN1 sideroflexin 1 -2.22641
DHRS4 dehydrogenase/reductase (SDR family) member 4 -2.22349
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.22238
SEPHS1 selenophosphate synthetase 1 -2.22098
MRPL48 mitochondrial ribosomal protein L48 -2.22002
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.21989
GFUS GDP-L-fucose synthase -2.21968
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -2.21304
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -2.21233
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.20925
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.2084
OCEL1 occludin/ELL domain containing 1 -2.20822
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -2.20742
MSH6 mutS homolog 6 -2.20191
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -2.20105
FANCI Fanconi anemia, complementation group I -2.20081
RBM28 RNA binding motif protein 28 -2.20066
TIMELESS timeless circadian clock -2.19717
NSD1 nuclear receptor binding SET domain protein 1 -2.19679
ATAD2 ATPase family, AAA domain containing 2 -2.19592
TUBGCP5 tubulin, gamma complex associated protein 5 -2.19565
CDT1 chromatin licensing and DNA replication factor 1 -2.19434
KIF3A kinesin family member 3A -2.1934
METTL18 methyltransferase like 18 -2.19275
HSPA14 heat shock 70kDa protein 14 -2.19183
CDC23 cell division cycle 23 -2.19089
TBPL1 TBP-like 1 -2.19055
MSH2 mutS homolog 2 -2.1901
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.18934
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.18933
MCMBP minichromosome maintenance complex binding protein -2.1887
CDV3 CDV3 homolog (mouse) -2.18798
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -2.18361
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.18232
CKS2 CDC28 protein kinase regulatory subunit 2 -2.1806
CBFB core-binding factor, beta subunit -2.17895
NOL8 nucleolar protein 8 -2.17882
ZNF302 zinc finger protein 302 -2.17757
GALP galanin-like peptide -2.17745
NR2F1 nuclear receptor subfamily 2, group F, member 1 -2.17705
ZSCAN5A zinc finger and SCAN domain containing 5A -2.17684
SQLE squalene epoxidase -2.17471
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -2.17377
DPP3 dipeptidyl-peptidase 3 -2.17351
CHUK conserved helix-loop-helix ubiquitous kinase -2.16899
C8A complement component 8, alpha polypeptide -2.16866
GPS2 G protein pathway suppressor 2 -2.16796
SURF2 surfeit 2 -2.16616
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.16581
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -2.16513
SPATA5L1 spermatogenesis associated 5-like 1 -2.16418
STIL SCL/TAL1 interrupting locus -2.16214
GEMIN4 gem (nuclear organelle) associated protein 4 -2.16129
RMI1 RecQ mediated genome instability 1 -2.15796
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -2.15742
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.15698
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -2.15591
WDR12 WD repeat domain 12 -2.1546
THOP1 thimet oligopeptidase 1 -2.15414
CASP6 caspase 6, apoptosis-related cysteine peptidase -2.15164
TEDC2 tubulin epsilon and delta complex 2 -2.14847
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -2.14447
ZNF207 zinc finger protein 207 -2.14206
KIF18B kinesin family member 18B -2.14116
ZC3H14 zinc finger CCCH-type containing 14 -2.13849
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.13727
MBIP MAP3K12 binding inhibitory protein 1 -2.13486
ARHGAP11A Rho GTPase activating protein 11A -2.13201
FTCD formimidoyltransferase cyclodeaminase -2.13196
NRF1 nuclear respiratory factor 1 -2.13048
MGP matrix Gla protein -2.12956
SPARCL1 SPARC-like 1 (hevin) -2.12929
ACOD1 aconitate decarboxylase 1 -2.12912
CENPU centromere protein U -2.12871
GID8 GID complex subunit 8 -2.12792
TRA2B transformer 2 beta homolog (Drosophila) -2.12145
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -2.12142
SUMF2 sulfatase modifying factor 2 -2.12108
RBM3 RNA binding motif (RNP1, RRM) protein 3 -2.12028
MRPS31 mitochondrial ribosomal protein S31 -2.11791
AFM afamin -2.11659
NUP37 nucleoporin 37kDa -2.11557
NCAPD2 non-SMC condensin I complex, subunit D2 -2.11418
CRYZ crystallin, zeta (quinone reductase) -2.11392
SPA17 sperm autoantigenic protein 17 -2.11111
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.11095
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.11067
FTO fat mass and obesity associated -2.10703
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.10515
LSAMP limbic system-associated membrane protein -2.09969
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.09738
PPIG peptidylprolyl isomerase G (cyclophilin G) -2.09613
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -2.09542
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.09409
PLG plasminogen -2.09144
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.08951
EDIL3 EGF-like repeats and discoidin I-like domains 3 -2.08713
DHCR7 7-dehydrocholesterol reductase -2.08684
ARTN artemin -2.08639
SORD sorbitol dehydrogenase -2.08539
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.0849
FANCF Fanconi anemia, complementation group F -2.0846
CR2 complement component (3d/Epstein Barr virus) receptor 2 -2.08288
ZNF184 zinc finger protein 184 -2.07955
RBBP5 retinoblastoma binding protein 5 -2.07896
FOXM1 forkhead box M1 -2.07772
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.07614
UBIAD1 UbiA prenyltransferase domain containing 1 -2.07574
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.07384
SLIRP SRA stem-loop interacting RNA binding protein -2.07191
MYOC myocilin, trabecular meshwork inducible glucocorticoid response -2.07098
GIN1 gypsy retrotransposon integrase 1 -2.0709
AUNIP aurora kinase A and ninein interacting protein -2.07081
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -2.06912
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -2.06892
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.06743
PRMT1 protein arginine methyltransferase 1 -2.06703
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.06587
RBBP9 retinoblastoma binding protein 9 -2.06182
MANF mesencephalic astrocyte-derived neurotrophic factor -2.06128
SPAST spastin -2.06083
NID2 nidogen 2 (osteonidogen) -2.0595
HSPA4 heat shock 70kDa protein 4 -2.05761
RBM25 RNA binding motif protein 25 -2.05669
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -2.05621
PGRMC1 progesterone receptor membrane component 1 -2.05527
THBS4 thrombospondin 4 -2.05202
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.05093
ATG5 autophagy related 5 -2.05087
SERBP1 SERPINE1 mRNA binding protein 1 -2.05005
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -2.04987
ACACB acetyl-CoA carboxylase beta -2.04946
MRS2 MRS2 magnesium transporter -2.04924
NKAPD1 NKAP domain containing 1 -2.04883
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.04749
IVD isovaleryl-CoA dehydrogenase -2.04728
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -2.04626
ASDURF ASNSD1 upstream open reading frame -2.04551
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.04487
HYOU1 hypoxia up-regulated 1 -2.04343
NUP155 nucleoporin 155kDa -2.04333
CHMP6 charged multivesicular body protein 6 -2.04188
PUF60 poly-U binding splicing factor 60KDa -2.04187
PRC1 protein regulator of cytokinesis 1 -2.04002
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -2.03757
SLC39A7 solute carrier family 39 (zinc transporter), member 7 -2.03621
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -2.03594
LYSET lysosomal enzyme trafficking factor -2.03468
MYZAP myocardial zonula adherens protein -2.03457
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.03431
SPPL2A signal peptide peptidase like 2A -2.0342
CNOT9 CCR4-NOT transcription complex subunit 9 -2.03412
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.03412
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.03147
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -2.03024
FLRT3 fibronectin leucine rich transmembrane protein 3 -2.02743
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.02649
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.0223
GUF1 GUF1 GTPase homolog (S. cerevisiae) -2.02223
RAB4A RAB4A, member RAS oncogene family -2.02222
CEP43 centrosomal protein 43 -2.0197
CSNK1G2 casein kinase 1, gamma 2 -2.01721
HELLS helicase, lymphoid-specific -2.01461
RBM14-RBM4 RBM14-RBM4 readthrough -2.01372
ZNF668 zinc finger protein 668 -2.01281
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -2.01242
DSCC1 DNA replication and sister chromatid cohesion 1 -2.01079
MIS12 MIS12 kinetochore complex component -2.01028
GPT glutamic-pyruvate transaminase (alanine aminotransferase) -2.00648
AP4M1 adaptor-related protein complex 4, mu 1 subunit -2.00614
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like -2.00274