CRCGN015_HEPG2_48H:E19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n,n??=-diacetylbenzidine 102.27 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

56 genes differentially expressed following the CRCGN015_HEPG2_48H:E19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SP3 Sp3 transcription factor 2.33841
LAGE3 L antigen family, member 3 2.32639
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 2.23084
METRN meteorin, glial cell differentiation regulator 2.2223
CALCOCO2 calcium binding and coiled-coil domain 2 2.20933
RPS5 ribosomal protein S5 2.17796
CHMP6 charged multivesicular body protein 6 2.12903

decreased expression

Symbol Name Standardized Value
COG7 component of oligomeric golgi complex 7 -6.33961
MT1X metallothionein 1X -4.88994
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -3.32793
NPIPA6 nuclear pore complex interacting protein family, member A6 -2.84457
TEP1 telomerase-associated protein 1 -2.80503
FLCN folliculin -2.78697
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.73382
HSPA8 heat shock 70kDa protein 8 -2.71327
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -2.52708
MBTD1 mbt domain containing 1 -2.48269
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial -2.48265
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) -2.3825
MSMB microseminoprotein, beta- -2.36622
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.36531
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -2.29984
TRIM56 tripartite motif containing 56 -2.26918
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -2.26631
XPO7 exportin 7 -2.25313
FZD8 frizzled class receptor 8 -2.23299
MCUR1 mitochondrial calcium uniporter regulator 1 -2.20227
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -2.17954
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -2.16496
EHMT1 euchromatic histone-lysine N-methyltransferase 1 -2.15486
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -2.14041
ACE angiotensin I converting enzyme -2.1398
KATNIP katanin interacting protein -2.13888
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.13544
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain -2.12242
KRT17 keratin 17, type I -2.09247
LITAF lipopolysaccharide-induced TNF factor -2.09011
TBC1D22B TBC1 domain family, member 22B -2.0844
CXADR coxsackie virus and adenovirus receptor -2.07684
ERCC4 excision repair cross-complementation group 4 -2.07497
TGFB2 transforming growth factor, beta 2 -2.07067
TP53BP2 tumor protein p53 binding protein 2 -2.06198
IL10RB interleukin 10 receptor, beta -2.05285
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -2.05174
ABHD18 abhydrolase domain containing 18 -2.04779
PCDHA9 protocadherin alpha 9 -2.04747
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough -2.0472
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like -2.04604
ETV3 ets variant 3 -2.04526
PCDHGA1 protocadherin gamma subfamily A, 1 -2.03606
CLDN7 claudin 7 -2.02171
NAIP NLR family, apoptosis inhibitory protein -2.0217
ZNF669 zinc finger protein 669 -2.01711
FOXC2 forkhead box C2 -2.01503
AFDN afadin, adherens junction formation factor -2.01227
EPAS1 endothelial PAS domain protein 1 -2.00424