CRCGN015_HEPG2_48H:F03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diethylstilbestrol 11.16 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_HEPG2_48H:F03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IL4R interleukin 4 receptor 3.79288
SNAP25 synaptosomal-associated protein, 25kDa 3.28033
MINDY1 MINDY lysine 48 deubiquitinase 1 2.98766
SCRN1 secernin 1 2.77626
BLTP2 bridge-like lipid transfer protein family member 2 2.70532
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.4699
ARRB1 arrestin, beta 1 2.35459
CRELD2 cysteine-rich with EGF-like domains 2 2.33756
ATL2 atlastin GTPase 2 2.31894
TBPL1 TBP-like 1 2.26878
SDF2L1 stromal cell-derived factor 2-like 1 2.19328
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.11822
CCND1 cyclin D1 2.09193
FADD Fas (TNFRSF6)-associated via death domain 2.06681
PHF20L1 PHD finger protein 20-like 1 2.05661
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.03962
ENO2 enolase 2 (gamma, neuronal) 2.01076

decreased expression

Symbol Name Standardized Value
LAP3 leucine aminopeptidase 3 -3.59506
DIPK1A divergent protein kinase domain 1A -3.30788
RPIA ribose 5-phosphate isomerase A -3.21063
WASHC4 WASH complex subunit 4 -3.00885
MCUR1 mitochondrial calcium uniporter regulator 1 -2.84693
S100P S100 calcium binding protein P -2.54057
FBXO21 F-box protein 21 -2.51566
PLBD1 phospholipase B domain containing 1 -2.29637
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.22217
C1QB complement component 1, q subcomponent, B chain -2.21181
MT1X metallothionein 1X -2.12009
CHIC2 cysteine-rich hydrophobic domain 2 -2.07717
MAPK13 mitogen-activated protein kinase 13 -2.0715
GABARAP GABA(A) receptor-associated protein -2.03013