CRCGN015_HEPG2_48H:F10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cyclohexylamine.hcl 101.47 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_HEPG2_48H:F10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 3.52647
ANO10 anoctamin 10 3.10152
ZNF589 zinc finger protein 589 3.00584
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.9368
CDC25A cell division cycle 25A 2.63558
MYLK myosin light chain kinase 2.54529
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.29757
ZNF274 zinc finger protein 274 2.16944

decreased expression

Symbol Name Standardized Value
SNX7 sorting nexin 7 -3.53928
GOLT1B golgi transport 1B -3.49981
PLIN2 perilipin 2 -3.0149
PDLIM1 PDZ and LIM domain 1 -2.94558
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.7962
RECQL RecQ helicase-like -2.27013
MT1X metallothionein 1X -2.24573
HEBP1 heme binding protein 1 -2.21264
S100P S100 calcium binding protein P -2.11322