CRCGN015_HEPG2_48H:F12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cyclohexylamine.hcl 11.27 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_HEPG2_48H:F12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 4.57218
SNX11 sorting nexin 11 4.00478
SIRT3 sirtuin 3 3.29619
GRWD1 glutamate-rich WD repeat containing 1 2.95444
CBX1 chromobox homolog 1 2.71569
CTR9 CTR9, Paf1/RNA polymerase II complex component 2.33893
DEAF1 DEAF1 transcription factor 2.16883
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 2.14354
NECAB3 N-terminal EF-hand calcium binding protein 3 2.06688
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 2.06446
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 2.06442
LSR lipolysis stimulated lipoprotein receptor 2.04089
RHOG ras homolog family member G 2.01591

decreased expression

Symbol Name Standardized Value
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -4.28215
S100P S100 calcium binding protein P -3.3197
TM9SF3 transmembrane 9 superfamily member 3 -3.25731
CXADR coxsackie virus and adenovirus receptor -2.93128
TFRC transferrin receptor -2.92802
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.48453
IGFBP7 insulin-like growth factor binding protein 7 -2.15743
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -2.11854
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.02883