CRCGN015_HEPG2_48H:F18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description oxymetholone 11.33 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN015_HEPG2_48H:F18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RPP38 ribonuclease P/MRP 38kDa subunit 3.92736
MAP7 microtubule-associated protein 7 3.31488
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.1668
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.06455
CDC123 cell division cycle 123 3.02626
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.89883
HSPA14 heat shock 70kDa protein 14 2.8293
AATF apoptosis antagonizing transcription factor 2.24484
TUBA1C tubulin, alpha 1c 2.22925
BATF basic leucine zipper transcription factor, ATF-like 2.18911
RPL7A ribosomal protein L7a 2.17683
TXNRD1 thioredoxin reductase 1 2.15078
RPL37 ribosomal protein L37 2.13811
TIPIN TIMELESS interacting protein 2.12477
RPL6 ribosomal protein L6 2.08009
RPL27A ribosomal protein L27a 2.04542
UGDH UDP-glucose 6-dehydrogenase 2.02979
RPLP0 ribosomal protein, large, P0 2.0278
RPLP1 ribosomal protein, large, P1 2.02397
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 2.00144

decreased expression

Symbol Name Standardized Value
MT1X metallothionein 1X -4.18173
CXADR coxsackie virus and adenovirus receptor -3.85266
DCK deoxycytidine kinase -3.41409
TES testin LIM domain protein -3.2961
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.95964
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.79861
KIF20A kinesin family member 20A -2.59054
CSRP2 cysteine and glycine-rich protein 2 -2.54866
RAB3A RAB3A, member RAS oncogene family -2.22455
TM9SF3 transmembrane 9 superfamily member 3 -2.21441
CLCNKB chloride channel, voltage-sensitive Kb -2.17381
ANXA5 annexin A5 -2.17366
EVI2B ecotropic viral integration site 2B -2.16504
LAPTM4A lysosomal protein transmembrane 4 alpha -2.13955
RLN1 relaxin 1 -2.12234
APOH apolipoprotein H (beta-2-glycoprotein I) -2.08863
NEFL neurofilament, light polypeptide -2.01862