CRCGN015_HEPG2_48H:F20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description caffeic-acid 32.81 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_HEPG2_48H:F20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PLEKHJ1 pleckstrin homology domain containing, family J member 1 4.32149
COPS7A COP9 signalosome subunit 7A 3.46281
GTPBP8 GTP-binding protein 8 (putative) 2.9554
NOSIP nitric oxide synthase interacting protein 2.72375
LGMN legumain 2.58685
PRR7 proline rich 7 (synaptic) 2.53257
FHIT fragile histidine triad 2.02061
SYK spleen tyrosine kinase 2.01715

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -6.17697
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.74188
NCK1 NCK adaptor protein 1 -3.69267
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.62795
RHOB ras homolog family member B -3.31037
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.00343
TEX10 testis expressed 10 -2.23482
TSPAN4 tetraspanin 4 -2.17617
MCM3 minichromosome maintenance complex component 3 -2.16728
LINC02762 long intergenic non-protein coding RNA 2762 -2.14554
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.06094
TACC2 transforming, acidic coiled-coil containing protein 2 -2.01791