CRCGN015_HEPG2_48H:G03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nifedipine 11.22 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_HEPG2_48H:G03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
VGLL4 vestigial-like family member 4 4.6213
TCTN1 tectonic family member 1 2.78364
BAMBI BMP and activin membrane-bound inhibitor 2.08486
GRB10 growth factor receptor-bound protein 10 2.05246

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.93516
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -4.2754
NCK1 NCK adaptor protein 1 -3.93602
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -3.7128
PDLIM1 PDZ and LIM domain 1 -3.57948
LINC02762 long intergenic non-protein coding RNA 2762 -3.27398
CCNH cyclin H -3.26898
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.37845
GP1BA glycoprotein Ib (platelet), alpha polypeptide -2.1144
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.09721
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 -2.06406
HOXB2 homeobox B2 -2.02071