CRCGN015_HEPG2_48H:G07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-chloroacetophenone 101.98 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_HEPG2_48H:G07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MOK MOK protein kinase 4.88295
GSTZ1 glutathione S-transferase zeta 1 4.5622
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 4.05406
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.76333
MPZL1 myelin protein zero-like 1 2.55241
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.47862
FZD7 frizzled class receptor 7 2.43829
DPP3 dipeptidyl-peptidase 3 2.36953
PARL presenilin associated, rhomboid-like 2.36015
BYSL bystin-like 2.28485
RABL3 RAB, member of RAS oncogene family-like 3 2.01356
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 2.01257

decreased expression

Symbol Name Standardized Value
TM9SF3 transmembrane 9 superfamily member 3 -5.36372
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -5.06679
THAP11 THAP domain containing 11 -4.94852
JMJD6 jumonji domain containing 6 -2.90842
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.70762
LOC124907782 dual specificity protein phosphatase 22 -2.55871
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.522
AURKB aurora kinase B -2.44171
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -2.36644
EVI2B ecotropic viral integration site 2B -2.06844
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -2.00573