CRCGN015_HEPG2_48H:G09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-chloroacetophenone 11.33 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_HEPG2_48H:G09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BACE2 beta-site APP-cleaving enzyme 2 4.48114
COPS7A COP9 signalosome subunit 7A 3.79477
SCAND1 SCAN domain containing 1 3.49278
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.34049
SLC75A1 solute carrier family 75 member 1 2.79988
PKN1 protein kinase N1 2.23725
KIFBP kinesin family binding protein 2.14956
IDE insulin-degrading enzyme 2.07634

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -4.80354
LOC124907782 dual specificity protein phosphatase 22 -2.91501
UFM1 ubiquitin-fold modifier 1 -2.42045
CENPE centromere protein E, 312kDa -2.40358
MSH6 mutS homolog 6 -2.22128
RHOB ras homolog family member B -2.2207
PELI1 pellino E3 ubiquitin protein ligase 1 -2.07495
SLC35E2B solute carrier family 35, member E2B -2.04636