CRCGN015_HEPG2_48H:G12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosopyrrolidine 11.67 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_HEPG2_48H:G12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ANO10 anoctamin 10 3.52132
LOC122526780 uncharacterized LOC122526780 3.21349
MSRA methionine sulfoxide reductase A 3.11652
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.95451
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.30284
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.15462

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -3.65832
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.97733
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.82086
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.21647
LOC124907782 dual specificity protein phosphatase 22 -2.15427
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -2.00198