CRCGN015_HEPG2_48H:G22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4,8-dihydroxy-2-quinolinecarboxylic acid 99.88 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_HEPG2_48H:G22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 4.72185
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.08438
TXNL4B thioredoxin-like 4B 3.29015
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.6318
CXCR4 chemokine (C-X-C motif) receptor 4 2.56429
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.129

decreased expression

Symbol Name Standardized Value
BIRC2 baculoviral IAP repeat containing 2 -4.08986
CXADR coxsackie virus and adenovirus receptor -3.82548
TM9SF2 transmembrane 9 superfamily member 2 -2.76382
SYNGAP1 synaptic Ras GTPase activating protein 1 -2.59841
MRPL33 mitochondrial ribosomal protein L33 -2.11175
RAI14 retinoic acid induced 14 -2.00244