CRCGN015_HEPG2_48H:G24 Gene Set

Dataset	Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category	transcriptomics
Type	small molecule perturbation
Description	4,8-dihydroxy-2-quinolinecarboxylic acid 11.1 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_HEPG2_48H:G24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol	Name	Standardized Value
NRDC	nardilysin convertase	2.2704
PIGB	phosphatidylinositol glycan anchor biosynthesis, class B	2.0573

decreased expression

Symbol	Name	Standardized Value
CXADR	coxsackie virus and adenovirus receptor	-6.093
CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)	-5.29005
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	-4.88835
MT1X	metallothionein 1X	-3.95708
IGFBP7	insulin-like growth factor binding protein 7	-2.98945
CSRP2	cysteine and glycine-rich protein 2	-2.74367
MAFF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	-2.66338
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	-2.2003
LIMD1	LIM domains containing 1	-2.17445
R3HCC1L	R3H domain and coiled-coil containing 1-like	-2.05155