CRCGN015_HEPG2_48H:H07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-aminostilbene 100.39 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_HEPG2_48H:H07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STIMATE STIM activating enhancer 3.46121
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 3.16017
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.10991
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.51071
NUCB2 nucleobindin 2 2.42608
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 2.38519
GSTM2 glutathione S-transferase mu 2 (muscle) 2.28491
HMOX1 heme oxygenase 1 2.1868
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.13033
HYOU1 hypoxia up-regulated 1 2.12544
GSTM4 glutathione S-transferase mu 4 2.0796
OSGIN1 oxidative stress induced growth inhibitor 1 2.06934
CYB561D2 cytochrome b561 family, member D2 2.06685
SYNGR3 synaptogyrin 3 2.00061

decreased expression

Symbol Name Standardized Value
IER3 immediate early response 3 -4.2553
TRIB1 tribbles pseudokinase 1 -2.88458
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.50587
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.45226
RLF rearranged L-myc fusion -2.24264
SMNDC1 survival motor neuron domain containing 1 -2.15785
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -2.15116
FHL2 four and a half LIM domains 2 -2.04473