CRCGN015_HEPG2_48H:H09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-aminostilbene 11.15 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_HEPG2_48H:H09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MCOLN1 mucolipin 1 3.30977
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.70669
NUCB2 nucleobindin 2 2.1532
SECISBP2 SECIS binding protein 2 2.10741
ALG12 ALG12, alpha-1,6-mannosyltransferase 2.10728
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.09312

decreased expression

Symbol Name Standardized Value
MT1X metallothionein 1X -5.74887
CDC20 cell division cycle 20 -4.16988
RPA3 replication protein A3, 14kDa -3.82828
IGFBP7 insulin-like growth factor binding protein 7 -2.8007
TM9SF3 transmembrane 9 superfamily member 3 -2.77473
ADI1 acireductone dioxygenase 1 -2.32277
IER3 immediate early response 3 -2.10808
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.06018
PROM1 prominin 1 -2.03697