CRCGN015_HEPG2_48H:H11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description maleic hydrazide 33.1 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

10 genes differentially expressed following the CRCGN015_HEPG2_48H:H11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HDGFL3 HDGF like 3 2.63385
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.6142
KLHL21 kelch-like family member 21 2.00099

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.34684
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.25478
SNX7 sorting nexin 7 -3.21367
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.44194
MT1X metallothionein 1X -2.37705
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.23121
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.20657