CRCGN015_HEPG2_48H:H15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyl methacrylate 10.94 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_HEPG2_48H:H15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PDLIM1 PDZ and LIM domain 1 3.03564
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.97672
EVL Enah/Vasp-like 2.84921
PLSCR3 phospholipid scramblase 3 2.75315
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.73475
SPRR1B small proline-rich protein 1B 2.04616

decreased expression

Symbol Name Standardized Value
BIRC2 baculoviral IAP repeat containing 2 -4.29424
MCM3 minichromosome maintenance complex component 3 -4.10034
TM9SF3 transmembrane 9 superfamily member 3 -3.62835
ENOPH1 enolase-phosphatase 1 -3.08446
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.92593
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.50089
EIF5 eukaryotic translation initiation factor 5 -2.29368
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.17642