CRCGN015_HEPG2_48H:H17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-(chloromethyl)pyridine.hcl 33.15 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

8 genes differentially expressed following the CRCGN015_HEPG2_48H:H17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SCRN1 secernin 1 5.93273
HMGA2 high mobility group AT-hook 2 2.514
PFKL phosphofructokinase, liver 2.13767

decreased expression

Symbol Name Standardized Value
FASTKD5 FAST kinase domains 5 -3.63127
S100P S100 calcium binding protein P -2.27144
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.17314
PLS1 plastin 1 -2.09005
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -2.04336