CRCGN015_HEPG2_48H:H20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description estradiol 34.78 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN015_HEPG2_48H:H20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MINDY1 MINDY lysine 48 deubiquitinase 1 5.50507
BAD BCL2-associated agonist of cell death 4.37219
NOSIP nitric oxide synthase interacting protein 3.59691
NUCB2 nucleobindin 2 3.00455
TMEM109 transmembrane protein 109 2.77803
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 2.51037
ZW10 zw10 kinetochore protein 2.42115
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.39097
FICD FIC domain containing 2.28195
CHEK2 checkpoint kinase 2 2.23399
BCR breakpoint cluster region 2.20473
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.12966
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.11935
TMCC1 transmembrane and coiled-coil domain family 1 2.05785
TXLNA taxilin alpha 2.01223

decreased expression

Symbol Name Standardized Value
PUF60 poly-U binding splicing factor 60KDa -4.74542
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.94023
PIGB phosphatidylinositol glycan anchor biosynthesis, class B -2.89296
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.38209
TM9SF3 transmembrane 9 superfamily member 3 -2.37114
ZNF282 zinc finger protein 282 -2.35748
MEPCE methylphosphate capping enzyme -2.31571
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.25688
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.16367
SCRN1 secernin 1 -2.15108
GREM2 gremlin 2, DAN family BMP antagonist -2.10942
LORICRIN loricrin cornified envelope precursor protein -2.10562
RHOF ras homolog family member F (in filopodia) -2.08947
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.07498
UNC13D unc-13 homolog D (C. elegans) -2.07132
MRGBP MRG/MORF4L binding protein -2.07095
TOE1 target of EGR1, member 1 (nuclear) -2.04618
MPV17L-BMERB1 MPV17L-BMERB1 readthrough -2.03562
ZNF668 zinc finger protein 668 -2.0304
PANK4 pantothenate kinase 4 -2.00917
LOC112694756 uncharaterized LOC112694756 -2.00328