CRCGN015_HEPG2_48H:H21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description estradiol 11.59 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_HEPG2_48H:H21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.60565
SMIM40 small integral membrane protein 40 3.16497
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.94144
ANO10 anoctamin 10 2.69483
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.13775
NCSTN nicastrin 2.0778

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -4.56133
FAIM Fas apoptotic inhibitory molecule -4.4606
LDHD lactate dehydrogenase D -3.6048
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.0467
EIF5 eukaryotic translation initiation factor 5 -2.78443
BCAP29 B-cell receptor-associated protein 29 -2.21041
PROM1 prominin 1 -2.06079
TEX10 testis expressed 10 -2.0212