| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | CH-223191 33.62 um perturbation at 48 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN015_HEPG2_48H:H23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IL4R | interleukin 4 receptor | 5.08275 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 4.25066 |
| TRIB3 | tribbles pseudokinase 3 | 3.88449 |
| METRN | meteorin, glial cell differentiation regulator | 3.46331 |
| EPHB2 | EPH receptor B2 | 3.43056 |
| SQSTM1 | sequestosome 1 | 3.05076 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.95849 |
| TRIB1 | tribbles pseudokinase 1 | 2.8954 |
| EGR1 | early growth response 1 | 2.81878 |
| ZFP36 | ZFP36 ring finger protein | 2.72825 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 2.72774 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 2.72256 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 2.64719 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 2.54994 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.52165 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.49797 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 2.41934 |
| PPOX | protoporphyrinogen oxidase | 2.41485 |
| HSPA13 | heat shock protein 70kDa family, member 13 | 2.40883 |
| UBQLN2 | ubiquilin 2 | 2.38802 |
| LOC102724560 | cystathionine beta-synthase | 2.38095 |
| ACOT9 | acyl-CoA thioesterase 9 | 2.37236 |
| CBX4 | chromobox homolog 4 | 2.20506 |
| FANCE | Fanconi anemia, complementation group E | 2.13924 |
| FZD1 | frizzled class receptor 1 | 2.13145 |
| TSC22D1 | TSC22 domain family, member 1 | 2.13034 |
| GARS1 | glycyl-tRNA synthetase 1 | 2.11796 |
| IER3 | immediate early response 3 | 2.10971 |
| AARS1 | alanyl-tRNA synthetase 1 | 2.10183 |
| CHN1 | chimerin 1 | 2.1018 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.03152 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 2.02774 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB1 | cyclin B1 | -3.93722 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | -3.49799 |
| PROM1 | prominin 1 | -3.47842 |
| SESN1 | sestrin 1 | -3.27263 |
| LYPLA1 | lysophospholipase I | -3.19374 |
| AURKB | aurora kinase B | -2.89453 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.85654 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.84023 |
| PDLIM1 | PDZ and LIM domain 1 | -2.82297 |
| RAB1B | RAB1B, member RAS oncogene family | -2.53388 |
| HMOX1 | heme oxygenase 1 | -2.46294 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.41381 |
| HSPB2 | heat shock 27kDa protein 2 | -2.37786 |
| PTCD2 | pentatricopeptide repeat domain 2 | -2.35233 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -2.3316 |
| PGAM4 | phosphoglycerate mutase family member 4 | -2.31927 |
| MRPL15 | mitochondrial ribosomal protein L15 | -2.31496 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) | -2.30169 |
| STMN1 | stathmin 1 | -2.28285 |
| SYT2 | synaptotagmin II | -2.26813 |
| TTK | TTK protein kinase | -2.26807 |
| BIRC5 | baculoviral IAP repeat containing 5 | -2.23819 |
| ZNF552 | zinc finger protein 552 | -2.22143 |
| CDC20 | cell division cycle 20 | -2.18286 |
| MEA1 | male-enhanced antigen 1 | -2.1686 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.1533 |
| F8 | coagulation factor VIII, procoagulant component | -2.10902 |
| ANAPC15 | anaphase promoting complex subunit 15 | -2.09244 |
| TMEM187 | transmembrane protein 187 | -2.09242 |
| CALCA | calcitonin-related polypeptide alpha | -2.08353 |
| AGBL5 | ATP/GTP binding protein-like 5 | -2.05614 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.04525 |
| LOC112694756 | uncharaterized LOC112694756 | -2.0445 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -2.03974 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -2.03007 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 | -2.02092 |
| AMT | aminomethyltransferase | -2.0172 |
| CCNG1 | cyclin G1 | -2.01017 |
