CRCGN015_HEPG2_48H:I03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzyl-alcohol 11.11 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_HEPG2_48H:I03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
C2CD2 C2 calcium-dependent domain containing 2 4.38817
EPN2 epsin 2 4.23774
VAV3 vav 3 guanine nucleotide exchange factor 2.8653
MAP2K5 mitogen-activated protein kinase kinase 5 2.72348
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.41097
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 2.25858
NCAPD2 non-SMC condensin I complex, subunit D2 2.1818
UBE3B ubiquitin protein ligase E3B 2.13783
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 2.13662
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 2.00875

decreased expression

Symbol Name Standardized Value
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -5.52291
CRK v-crk avian sarcoma virus CT10 oncogene homolog -4.34616
WDR13 WD repeat domain 13 -2.16708
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.0162