CRCGN015_HEPG2_48H:I05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description monoethylhexylphthalate 33.66 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

44 genes differentially expressed following the CRCGN015_HEPG2_48H:I05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.53729
LGMN legumain 3.13271
PLSCR3 phospholipid scramblase 3 2.78059
TLR6 toll-like receptor 6 2.73389
ITPKA inositol-trisphosphate 3-kinase A 2.71684
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.46084
SNX11 sorting nexin 11 2.43831
TMLHE trimethyllysine hydroxylase, epsilon 2.41452
LSR lipolysis stimulated lipoprotein receptor 2.3618
DENND1C DENN/MADD domain containing 1C 2.34211
PRR7 proline rich 7 (synaptic) 2.31465
MAMLD1 mastermind-like domain containing 1 2.31135
GTPBP8 GTP-binding protein 8 (putative) 2.27544
VSTM4 V-set and transmembrane domain containing 4 2.26344
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.23333
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 2.23036
DENND5B DENN/MADD domain containing 5B 2.22782
SYTL2 synaptotagmin-like 2 2.19845
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.1842
CREB5 cAMP responsive element binding protein 5 2.18072
NPTXR neuronal pentraxin receptor 2.16918
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 2.14726
SIRT3 sirtuin 3 2.13252
TAS2R4 taste receptor, type 2, member 4 2.12944
IGSF1 immunoglobulin superfamily, member 1 2.12476
NOD1 nucleotide-binding oligomerization domain containing 1 2.1017
AAMDC adipogenesis associated, Mth938 domain containing 2.09562
CPLX2 complexin 2 2.08645
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.04521
EPHA4 EPH receptor A4 2.04252
FRAS1 Fraser extracellular matrix complex subunit 1 2.04216
ADGRE3 adhesion G protein-coupled receptor E3 2.03883
C2CD2 C2 calcium-dependent domain containing 2 2.03672
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.01394
LYRM9 LYR motif containing 9 2.0065
UNC5C unc-5 homolog C (C. elegans) 2.00262

decreased expression

Symbol Name Standardized Value
DUSP6 dual specificity phosphatase 6 -4.157
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.2654
ADI1 acireductone dioxygenase 1 -3.14362
S100P S100 calcium binding protein P -2.71919
FASTKD5 FAST kinase domains 5 -2.66409
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.62887
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -2.23326
VAT1 vesicle amine transport 1 -2.21854