CRCGN015_HEPG2_48H:I09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenformin 11.16 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_HEPG2_48H:I09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FPGS folylpolyglutamate synthase 3.35581
MAP7 microtubule-associated protein 7 3.2943
RFC2 replication factor C (activator 1) 2, 40kDa 2.71084
PLSCR3 phospholipid scramblase 3 2.00856

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -2.77532
ANXA5 annexin A5 -2.62897
NUSAP1 nucleolar and spindle associated protein 1 -2.62163
CDC25B cell division cycle 25B -2.54395
S100P S100 calcium binding protein P -2.53293
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.48089
MRPS16 mitochondrial ribosomal protein S16 -2.44855
GGPS1 geranylgeranyl diphosphate synthase 1 -2.29529
SEC24C SEC24 family member C -2.23602
DYNLT3 dynein, light chain, Tctex-type 3 -2.13536