CRCGN015_HEPG2_48H:I12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aroclor 1260 10.65 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_HEPG2_48H:I12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBE2A ubiquitin-conjugating enzyme E2A 3.77966
ABHD6 abhydrolase domain containing 6 3.47084
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.67279
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.28534
EVL Enah/Vasp-like 2.12918
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 2.10076
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.06638

decreased expression

Symbol Name Standardized Value
THAP11 THAP domain containing 11 -4.87033
LYPLA1 lysophospholipase I -4.04657
S100P S100 calcium binding protein P -3.98255
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -3.74175
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.72786
WASHC4 WASH complex subunit 4 -3.4843
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.93371
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.83741
PECR peroxisomal trans-2-enoyl-CoA reductase -2.81936
NKIRAS2 NFKB inhibitor interacting Ras-like 2 -2.49632
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.32583
BNC2 basonuclin 2 -2.22519
MRPL15 mitochondrial ribosomal protein L15 -2.20543
IGFBP7 insulin-like growth factor binding protein 7 -2.15447
CTBS chitobiase, di-N-acetyl- -2.00709