CRCGN015_HEPG2_48H:I13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description toluene diisocyanate 101.79 um perturbation at 48 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

31 genes differentially expressed following the CRCGN015_HEPG2_48H:I13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SCRN1 secernin 1 3.85086
CXCR4 chemokine (C-X-C motif) receptor 4 3.23811
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 3.22597
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 3.00494
MYLK myosin light chain kinase 2.92924
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.68084
CDPF1 cysteine-rich, DPF motif domain containing 1 2.62073
DUSP6 dual specificity phosphatase 6 2.37358
RALB v-ral simian leukemia viral oncogene homolog B 2.32899
ABHD6 abhydrolase domain containing 6 2.3
CEMIP2 cell migration inducing hyaluronidase 2 2.28945
FHL2 four and a half LIM domains 2 2.22149
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.19771
SOX4 SRY (sex determining region Y)-box 4 2.18182
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.11198
DSG2 desmoglein 2 2.04711
LOC127933115 uncharacterized LOC127933115 2.02515
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 2.02447

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -3.93226
MCM3 minichromosome maintenance complex component 3 -3.52418
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.5107
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.07212
EIF5 eukaryotic translation initiation factor 5 -3.03553
NT5DC2 5'-nucleotidase domain containing 2 -2.50973
NUCB2 nucleobindin 2 -2.34957
CD58 CD58 molecule -2.31471
NUP85 nucleoporin 85kDa -2.17107
TFRC transferrin receptor -2.10687
AURKB aurora kinase B -2.08572
SLC66A2 solute carrier family 66 member 2 -2.0374
TEDC2 tubulin epsilon and delta complex 2 -2.03392