CRCGN015_HEPG2_48H:I15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description toluene diisocyanate 11.31 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_HEPG2_48H:I15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.90288
EAPP E2F-associated phosphoprotein 3.88717
C2CD2 C2 calcium-dependent domain containing 2 3.5431
STIMATE STIM activating enhancer 2.97873
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.5726

decreased expression

Symbol Name Standardized Value
COG7 component of oligomeric golgi complex 7 -4.44207
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.62823
MT1X metallothionein 1X -2.55642
COL21A1 collagen, type XXI, alpha 1 -2.37086
SMC1A structural maintenance of chromosomes 1A -2.25445
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.19506
TRIM56 tripartite motif containing 56 -2.12327
IGF2 insulin-like growth factor 2 -2.03247
FLCN folliculin -2.02941
CHAD chondroadherin -2.02825