CRCGN015_HEPG2_48H:I23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tryptophan 33.66 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_HEPG2_48H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RFC2 replication factor C (activator 1) 2, 40kDa 3.64458
PLSCR3 phospholipid scramblase 3 3.27716
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.23328
SLC75A1 solute carrier family 75 member 1 2.75064
ZFP36 ZFP36 ring finger protein 2.67148
MPZL1 myelin protein zero-like 1 2.56733
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.33685
KLHL21 kelch-like family member 21 2.29941
ETFB electron-transfer-flavoprotein, beta polypeptide 2.17014
SCRN1 secernin 1 2.11989
CSK c-src tyrosine kinase 2.10133
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.02902
CIDEB cell death-inducing DFFA-like effector b 2.02535
VAT1 vesicle amine transport 1 2.02237
LOC102724652 alpha-crystallin A chain 2.00222

decreased expression

Symbol Name Standardized Value
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.61002
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -3.69251
RPA3 replication protein A3, 14kDa -3.35913
MT1X metallothionein 1X -3.04638
NCK1 NCK adaptor protein 1 -2.90997
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.90307
UGDH UDP-glucose 6-dehydrogenase -2.82279
FASTKD5 FAST kinase domains 5 -2.37268
TM9SF3 transmembrane 9 superfamily member 3 -2.26806
ZDHHC4 zinc finger, DHHC-type containing 4 -2.2369
HAX1 HCLS1 associated protein X-1 -2.23285
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 -2.19034
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) -2.18721
UBL5 ubiquitin-like 5 -2.01255