CRCGN015_HEPG2_48H:J06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinyl toluene 11.11 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_HEPG2_48H:J06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MCOLN1 mucolipin 1 4.47452
CCNA1 cyclin A1 4.42173
CNPY3 canopy FGF signaling regulator 3 4.26668
AMDHD2 amidohydrolase domain containing 2 4.14494
CGB8 chorionic gonadotropin, beta polypeptide 8 2.95497
SLC75A1 solute carrier family 75 member 1 2.94019
CD5L CD5 molecule-like 2.20615
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 2.15025
DAPK3 death-associated protein kinase 3 2.1209
CCL13 chemokine (C-C motif) ligand 13 2.10654
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 2.07868
PNPLA6 patatin-like phospholipase domain containing 6 2.05353
ZNF266 zinc finger protein 266 2.0459
SSTR5 somatostatin receptor 5 2.02919
PRR5L proline rich 5 like 2.01647
FUS FUS RNA binding protein 2.01069
MEA1 male-enhanced antigen 1 2.00362
METTL16 methyltransferase like 16 2.00163

decreased expression

Symbol Name Standardized Value
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -4.44983
FHL2 four and a half LIM domains 2 -4.38006
YME1L1 YME1-like 1 ATPase -3.80992
CD58 CD58 molecule -3.34161
ABI1 abl-interactor 1 -2.634
KIAA0319L KIAA0319-like -2.33705
PRPF18 pre-mRNA processing factor 18 -2.22427
MT1X metallothionein 1X -2.19937
WAC WW domain containing adaptor with coiled-coil -2.16342
PLIN2 perilipin 2 -2.14907
ARHGAP12 Rho GTPase activating protein 12 -2.00165