CRCGN015_HEPG2_48H:J09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethinyl estradiol 11.03 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_HEPG2_48H:J09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FRS2 fibroblast growth factor receptor substrate 2 4.02049
LAGE3 L antigen family, member 3 3.61284
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.23381
PMM2 phosphomannomutase 2 3.16423
NCAPD2 non-SMC condensin I complex, subunit D2 2.34537
PLA2G1B phospholipase A2, group IB (pancreas) 2.17315
FPGS folylpolyglutamate synthase 2.15574
CEMIP2 cell migration inducing hyaluronidase 2 2.12139
NUP107 nucleoporin 107kDa 2.11388
CNOT2 CCR4-NOT transcription complex, subunit 2 2.06018
NNMT nicotinamide N-methyltransferase 2.02521

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -5.68981
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.96969
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.43981
DIPK1A divergent protein kinase domain 1A -4.41922
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.86466
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.82115
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.38834
TSC22D4 TSC22 domain family, member 4 -2.30103
KIF14 kinesin family member 14 -2.28836
GLRX2 glutaredoxin 2 -2.12274
INPP1 inositol polyphosphate-1-phosphatase -2.1067
ZMAT4 zinc finger, matrin-type 4 -2.0207