CRCGN015_HEPG2_48H:J11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tretinoin 33.43 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN015_HEPG2_48H:J11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HOXA5 homeobox A5 5.60324
SSBP2 single-stranded DNA binding protein 2 3.27348
HLA-DRA major histocompatibility complex, class II, DR alpha 3.27188
KLHDC2 kelch domain containing 2 3.15782
PDLIM1 PDZ and LIM domain 1 3.15658
TSKU tsukushi, small leucine rich proteoglycan 3.00461
SNAP25 synaptosomal-associated protein, 25kDa 2.97539
HOXA4 homeobox A4 2.94236
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.89263
C5 complement component 5 2.74192
SYNE2 spectrin repeat containing, nuclear envelope 2 2.52205
USP18 ubiquitin specific peptidase 18 2.41617
PMM2 phosphomannomutase 2 2.38381
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.22905
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.18277
IFI44L interferon-induced protein 44-like 2.14348
APOE apolipoprotein E 2.11403
OCRL oculocerebrorenal syndrome of Lowe 2.11071
HOXA7 homeobox A7 2.07662
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.05031
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.04808
AMPH amphiphysin 2.01139

decreased expression

Symbol Name Standardized Value
DUSP6 dual specificity phosphatase 6 -4.27604
IER3 immediate early response 3 -3.57383
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -3.24444
HMGA2 high mobility group AT-hook 2 -2.88688
MT1X metallothionein 1X -2.86567
TM9SF3 transmembrane 9 superfamily member 3 -2.57392
DCK deoxycytidine kinase -2.51251
FAT1 FAT atypical cadherin 1 -2.35211
RNF43 ring finger protein 43 -2.34473
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.28813
NGRN neugrin, neurite outgrowth associated -2.0921
CST1 cystatin SN -2.03095