CRCGN015_HEPG2_48H:J12 Gene Set
Genes
41 genes differentially expressed following the CRCGN015_HEPG2_48H:J12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HOXA5
|
homeobox A5
|
5.41041
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
3.7843
|
|
FPGS
|
folylpolyglutamate synthase
|
3.16904
|
|
SPAG4
|
sperm associated antigen 4
|
3.15571
|
|
KLHDC2
|
kelch domain containing 2
|
3.14214
|
|
C5
|
complement component 5
|
3.13171
|
|
PDLIM1
|
PDZ and LIM domain 1
|
3.12475
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.06545
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.87593
|
|
FZD7
|
frizzled class receptor 7
|
2.79089
|
|
MEF2C
|
myocyte enhancer factor 2C
|
2.6114
|
|
ECH1
|
enoyl CoA hydratase 1, peroxisomal
|
2.45187
|
|
HOXA7
|
homeobox A7
|
2.36576
|
|
HOXA4
|
homeobox A4
|
2.35059
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
2.32079
|
|
APOE
|
apolipoprotein E
|
2.30265
|
|
PYGL
|
phosphorylase, glycogen, liver
|
2.26537
|
|
RTL10
|
retrotransposon Gag like 10
|
2.24556
|
|
THTPA
|
thiamine triphosphatase
|
2.2236
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
2.17637
|
|
GSTM2
|
glutathione S-transferase mu 2 (muscle)
|
2.07544
|
|
SFTPB
|
surfactant protein B
|
2.03962
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IER3
|
immediate early response 3
|
-3.79763
|
|
DUSP6
|
dual specificity phosphatase 6
|
-3.69715
|
|
MT1X
|
metallothionein 1X
|
-2.94547
|
|
HMGA2
|
high mobility group AT-hook 2
|
-2.89227
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-2.78995
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-2.64928
|
|
SOX17
|
SRY (sex determining region Y)-box 17
|
-2.41672
|
|
FAT1
|
FAT atypical cadherin 1
|
-2.3409
|
|
CETN3
|
centrin, EF-hand protein, 3
|
-2.30167
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.29975
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
-2.23534
|
|
GNG11
|
guanine nucleotide binding protein (G protein), gamma 11
|
-2.19067
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.14085
|
|
MAFF
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
|
-2.13456
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.12317
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.1185
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
-2.02847
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.02607
|
|
JAM3
|
junctional adhesion molecule 3
|
-2.00923
|
