CRCGN015_HEPG2_48H:J13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosodiethylamine 100.3 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

9 genes differentially expressed following the CRCGN015_HEPG2_48H:J13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.6953
CBR3 carbonyl reductase 3 4.52522
ATP11B ATPase, class VI, type 11B 2.30506

decreased expression

Symbol Name Standardized Value
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -4.46282
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.86417
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.41749
APOA2 apolipoprotein A-II -2.67565
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.66111
TBC1D31 TBC1 domain family, member 31 -2.44694