CRCGN015_HEPG2_48H:J15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosodiethylamine 11.14 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_HEPG2_48H:J15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PRR15L proline rich 15-like 4.18285
FPGS folylpolyglutamate synthase 3.99478
ICAM3 intercellular adhesion molecule 3 3.82778
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.33094

decreased expression

Symbol Name Standardized Value
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -4.83243
TXNDC9 thioredoxin domain containing 9 -4.76982
PLIN2 perilipin 2 -3.91478
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.70563
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.7026
REV1 REV1, polymerase (DNA directed) -2.66265
UNC50 unc-50 homolog (C. elegans) -2.6561
TMEM131 transmembrane protein 131 -2.59688
NPDC1 neural proliferation, differentiation and control, 1 -2.56223
TMEM127 transmembrane protein 127 -2.44917
DRC4 dynein regulatory complex subunit 4 -2.33484
COX5B cytochrome c oxidase subunit Vb -2.28306
PDCL3 phosducin-like 3 -2.1833
CXXC1 CXXC finger protein 1 -2.03455
PDCD1 programmed cell death 1 -2.0316
SAP130 Sin3A-associated protein, 130kDa -2.01104
TXNL1 thioredoxin-like 1 -2.00695