CRCGN015_HEPG2_48H:J18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-(1-naphthyl)ethylenediamine.2hcl 11.22 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_HEPG2_48H:J18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SCRN1 secernin 1 4.22248
KLHL21 kelch-like family member 21 2.9712
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.85503
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.57152
METRN meteorin, glial cell differentiation regulator 2.51399
COQ8A coenzyme Q8A 2.13837
EAPP E2F-associated phosphoprotein 2.06701
STAP2 signal transducing adaptor family member 2 2.0411
SCAND1 SCAN domain containing 1 2.00569

decreased expression

Symbol Name Standardized Value
MT1X metallothionein 1X -4.65016
CXADR coxsackie virus and adenovirus receptor -4.55501
DERA deoxyribose-phosphate aldolase (putative) -3.12704
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -3.03456
IGFBP7 insulin-like growth factor binding protein 7 -3.01134
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.88753
TFRC transferrin receptor -2.48276
HEATR1 HEAT repeat containing 1 -2.47243
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.44451
SRGN serglycin -2.37031
CSRP2 cysteine and glycine-rich protein 2 -2.32824
CLDND1 claudin domain containing 1 -2.01853