CRCGN015_HEPG2_48H:J19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description simazine 102.07 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_HEPG2_48H:J19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KDM5A lysine (K)-specific demethylase 5A 3.7847
PLSCR3 phospholipid scramblase 3 2.79429
MAP2K5 mitogen-activated protein kinase kinase 5 2.51089
FBXO31 F-box protein 31 2.34194
ST20-MTHFS ST20-MTHFS readthrough 2.30561
METTL1 methyltransferase like 1 2.08841

decreased expression

Symbol Name Standardized Value
C2CD5 C2 calcium-dependent domain containing 5 -4.59731
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.91632
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.37491
GADD45A growth arrest and DNA-damage-inducible, alpha -3.37473
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.02058
MT1X metallothionein 1X -2.91596
TM9SF3 transmembrane 9 superfamily member 3 -2.71502
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.49502
ETNK1 ethanolamine kinase 1 -2.38651
INTS13 integrator complex subunit 13 -2.27404
XPO7 exportin 7 -2.10867
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -2.06714
RECQL RecQ helicase-like -2.02658
GRN granulin -2.0124