CRCGN015_HEPG2_48H:J21 Gene Set
Genes
34 genes differentially expressed following the CRCGN015_HEPG2_48H:J21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PLSCR3
|
phospholipid scramblase 3
|
4.68788
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
4.14262
|
|
PFKL
|
phosphofructokinase, liver
|
3.6985
|
|
GATD3
|
glutamine amidotransferase class 1 domain containing 3
|
3.46731
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.14589
|
|
RBM15B
|
RNA binding motif protein 15B
|
3.11894
|
|
NOTCH1
|
notch 1
|
2.96026
|
|
UBE2G2
|
ubiquitin-conjugating enzyme E2G 2
|
2.58076
|
|
PWP2
|
PWP2 periodic tryptophan protein homolog (yeast)
|
2.57436
|
|
RBBP5
|
retinoblastoma binding protein 5
|
2.43653
|
|
SMU1
|
smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
|
2.40106
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
2.1704
|
|
HP1BP3
|
heterochromatin protein 1, binding protein 3
|
2.11822
|
|
TRAPPC10
|
trafficking protein particle complex 10
|
2.07719
|
|
MFAP2
|
microfibrillar-associated protein 2
|
2.06078
|
|
SERPINH1
|
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
|
2.04685
|
|
ZNF124
|
zinc finger protein 124
|
2.02013
|
|
MDM4
|
MDM4, p53 regulator
|
2.01107
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-5.08299
|
|
ANXA5
|
annexin A5
|
-4.2751
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-3.82936
|
|
ISOC1
|
isochorismatase domain containing 1
|
-3.7353
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-3.67557
|
|
APOO
|
apolipoprotein O
|
-2.72438
|
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-2.42303
|
|
RAI1
|
retinoic acid induced 1
|
-2.41464
|
|
CSF2RA
|
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
|
-2.18638
|
|
DHRS7B
|
dehydrogenase/reductase (SDR family) member 7B
|
-2.17417
|
|
LILRB4
|
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
|
-2.17036
|
|
SIL1
|
SIL1 nucleotide exchange factor
|
-2.10884
|
|
DNALI1
|
dynein, axonemal, light intermediate chain 1
|
-2.07497
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-2.07141
|
|
SPAG16
|
sperm associated antigen 16
|
-2.03237
|
|
CD63
|
CD63 molecule
|
-2.01446
|
