CRCGN015_HEPG2_48H:J24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2',5,5'-tetrachlorobenzidine 11.22 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

1020 genes differentially expressed following the CRCGN015_HEPG2_48H:J24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TRIB1 tribbles pseudokinase 1 7.07987
H2BC21 H2B clustered histone 21 6.60063
FHL2 four and a half LIM domains 2 6.53535
ACOT9 acyl-CoA thioesterase 9 6.06005
SOX4 SRY (sex determining region Y)-box 4 5.94548
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.7293
S100A4 S100 calcium binding protein A4 5.71909
IL4R interleukin 4 receptor 5.24229
NANOS3 nanos homolog 3 (Drosophila) 4.7794
FAT1 FAT atypical cadherin 1 4.57333
IER3 immediate early response 3 4.53486
GRB10 growth factor receptor-bound protein 10 4.45512
FOSL1 FOS-like antigen 1 4.39236
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 4.37051
CDPF1 cysteine-rich, DPF motif domain containing 1 4.10432
DSG2 desmoglein 2 4.05235
SLC75A1 solute carrier family 75 member 1 4.01683
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.99572
BCL10 B-cell CLL/lymphoma 10 3.97866
SOCS2 suppressor of cytokine signaling 2 3.86695
TOMM34 translocase of outer mitochondrial membrane 34 3.85133
TSPO translocator protein (18kDa) 3.84843
MAPK13 mitogen-activated protein kinase 13 3.7878
H2AC19 H2A clustered histone 19 3.74238
TMEM184B transmembrane protein 184B 3.68246
VAT1 vesicle amine transport 1 3.60069
RALB v-ral simian leukemia viral oncogene homolog B 3.58044
TIMP2 TIMP metallopeptidase inhibitor 2 3.54333
EPHA2 EPH receptor A2 3.48706
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 3.476
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 3.4525
CHIC2 cysteine-rich hydrophobic domain 2 3.42154
SNX11 sorting nexin 11 3.37695
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 3.36039
SFXN3 sideroflexin 3 3.34316
LOXL1 lysyl oxidase-like 1 3.32545
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 3.30345
S100A11 S100 calcium binding protein A11 3.30245
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 3.2982
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 3.2733
MVP major vault protein 3.26867
SQSTM1 sequestosome 1 3.26606
SLC35F2 solute carrier family 35, member F2 3.24023
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 3.22356
PROCR protein C receptor, endothelial 3.22275
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.21147
PPARG peroxisome proliferator-activated receptor gamma 3.19643
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 3.19472
USP3 ubiquitin specific peptidase 3 3.19453
MYH9 myosin, heavy chain 9, non-muscle 3.17253
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 3.12267
EXOC1 exocyst complex component 1 3.12263
AKAP12 A kinase (PRKA) anchor protein 12 3.11017
TUBB6 tubulin, beta 6 class V 3.10459
MOK MOK protein kinase 3.0832
WDR44 WD repeat domain 44 3.0552
TRIP4 thyroid hormone receptor interactor 4 3.04934
S100A6 S100 calcium binding protein A6 3.0456
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 3.03603
H2AC6 H2A clustered histone 6 3.0235
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 3.02067
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.01066
ZNF274 zinc finger protein 274 2.99856
NECAP2 NECAP endocytosis associated 2 2.99145
ZSCAN9 zinc finger and SCAN domain containing 9 2.98818
YEATS2 YEATS domain containing 2 2.98618
H2BC12 H2B clustered histone 12 2.9758
CTC1 CTS telomere maintenance complex component 1 2.97493
FYN FYN proto-oncogene, Src family tyrosine kinase 2.95943
TRIM13 tripartite motif containing 13 2.95492
TNIP2 TNFAIP3 interacting protein 2 2.95347
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.94008
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 2.91102
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.90846
PRDM4 PR domain containing 4 2.89034
DDRGK1 DDRGK domain containing 1 2.86227
GTF2B general transcription factor IIB 2.85789
KDM3A lysine (K)-specific demethylase 3A 2.85464
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.85442
EIF6 eukaryotic translation initiation factor 6 2.84695
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.83636
EHD4 EH-domain containing 4 2.8307
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.80732
NOP10 NOP10 ribonucleoprotein 2.8071
GABARAP GABA(A) receptor-associated protein 2.80641
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 2.7992
CEMIP2 cell migration inducing hyaluronidase 2 2.79591
RABAC1 Rab acceptor 1 (prenylated) 2.79517
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.78722
CLTB clathrin, light chain B 2.77312
RAB9A RAB9A, member RAS oncogene family 2.74705
MBD1 methyl-CpG binding domain protein 1 2.73233
BECN1 beclin 1, autophagy related 2.73224
BIK BCL2-interacting killer (apoptosis-inducing) 2.7297
MOSPD1 motile sperm domain containing 1 2.71384
ARHGAP29 Rho GTPase activating protein 29 2.69808
ZFP36 ZFP36 ring finger protein 2.69116
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.68476
TP53I3 tumor protein p53 inducible protein 3 2.68365
ATOSB atos homolog B 2.67814
MAP7D1 MAP7 domain containing 1 2.67663
REXO2 RNA exonuclease 2 2.67087
SARS1 seryl-tRNA synthetase 1 2.66999
KIF3C kinesin family member 3C 2.66991
ADAM9 ADAM metallopeptidase domain 9 2.66705
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.66199
JPT1 Jupiter microtubule associated homolog 1 2.65988
NME7 NME/NM23 family member 7 2.65245
MMRN2 multimerin 2 2.63597
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 2.63402
OVOL2 ovo-like zinc finger 2 2.6327
TRAFD1 TRAF-type zinc finger domain containing 1 2.62907
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.62873
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.62498
LRP10 low density lipoprotein receptor-related protein 10 2.62438
VPS9D1 VPS9 domain containing 1 2.62292
ATF3 activating transcription factor 3 2.62251
GLRX glutaredoxin (thioltransferase) 2.62194
RPF1 ribosome production factor 1 homolog (S. cerevisiae) 2.60711
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 2.60431
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.60193
CST7 cystatin F (leukocystatin) 2.57004
CD9 CD9 molecule 2.568
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.56722
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.55308
SPON2 spondin 2, extracellular matrix protein 2.55025
STX8 syntaxin 8 2.54373
MICALL1 MICAL-like 1 2.53581
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.5346
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.53188
EIF4A2 eukaryotic translation initiation factor 4A2 2.52459
ZNHIT6 zinc finger, HIT-type containing 6 2.52057
ORAI3 ORAI calcium release-activated calcium modulator 3 2.51892
BATF basic leucine zipper transcription factor, ATF-like 2.51354
INPP1 inositol polyphosphate-1-phosphatase 2.51353
RND3 Rho family GTPase 3 2.51055
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 2.50721
ARL14 ADP-ribosylation factor-like 14 2.48292
RMC1 regulator of MON1-CCZ1 2.48147
SRPX sushi-repeat containing protein, X-linked 2.4799
RHOC ras homolog family member C 2.47645
ACTN4 actinin, alpha 4 2.47506
CSNK1E casein kinase 1, epsilon 2.47298
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.47098
POLL polymerase (DNA directed), lambda 2.46232
WDR13 WD repeat domain 13 2.46099
EMC7 ER membrane protein complex subunit 7 2.44018
KRT18 keratin 18, type I 2.4313
EDN1 endothelin 1 2.42426
MYO5A myosin VA (heavy chain 12, myoxin) 2.42217
MAP1S microtubule-associated protein 1S 2.42131
GBA1 glucosylceramidase beta 1 2.42072
NFE2L1 nuclear factor, erythroid 2-like 1 2.41848
RAP1B RAP1B, member of RAS oncogene family 2.41599
JOSD1 Josephin domain containing 1 2.41533
ZFAND5 zinc finger, AN1-type domain 5 2.4137
YPEL5 yippee-like 5 (Drosophila) 2.41203
WDR47 WD repeat domain 47 2.41008
ARID5A AT rich interactive domain 5A (MRF1-like) 2.40802
CSRNP2 cysteine-serine-rich nuclear protein 2 2.40789
RRAGC Ras-related GTP binding C 2.40766
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 2.40624
ARHGAP12 Rho GTPase activating protein 12 2.39872
FAM50A family with sequence similarity 50, member A 2.39255
GPN2 GPN-loop GTPase 2 2.39178
MFSD1 major facilitator superfamily domain containing 1 2.38776
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.38328
TCEAL4 transcription elongation factor A (SII)-like 4 2.38176
H2BC5 H2B clustered histone 5 2.37344
AHNAK2 AHNAK nucleoprotein 2 2.37011
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.35708
RRAS related RAS viral (r-ras) oncogene homolog 2.352
TIMP1 TIMP metallopeptidase inhibitor 1 2.35042
PLSCR3 phospholipid scramblase 3 2.34956
TTC4 tetratricopeptide repeat domain 4 2.34761
GDI1 GDP dissociation inhibitor 1 2.34325
DSTN destrin (actin depolymerizing factor) 2.3385
VEGFC vascular endothelial growth factor C 2.3383
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 2.33574
BFSP1 beaded filament structural protein 1, filensin 2.3351
FAM32A family with sequence similarity 32, member A 2.32823
KDR kinase insert domain receptor 2.32339
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.32274
TSG101 tumor susceptibility 101 2.31824
MTCH1 mitochondrial carrier 1 2.31126
MAN2B2 mannosidase, alpha, class 2B, member 2 2.31116
RTL8A retrotransposon Gag like 8A 2.30703
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 2.30673
TM4SF1 transmembrane 4 L six family member 1 2.29999
ISG20 interferon stimulated exonuclease gene 20kDa 2.29699
PRKCD protein kinase C, delta 2.29539
TES testin LIM domain protein 2.28914
LMNA lamin A/C 2.28894
QTMAN queuosine-tRNA mannosyltransferase 2.27696
RRAGA Ras-related GTP binding A 2.27689
VGLL4 vestigial-like family member 4 2.27365
SEC61G Sec61 gamma subunit 2.27326
KLF4 Kruppel-like factor 4 (gut) 2.27048
LDOC1 leucine zipper, down-regulated in cancer 1 2.26577
TSPOAP1 TSPO associated protein 1 2.25908
CAB39 calcium binding protein 39 2.25319
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.25066
CD151 CD151 molecule (Raph blood group) 2.2481
MYO6 myosin VI 2.24537
LMBR1L limb development membrane protein 1-like 2.24483
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 2.23958
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.23886
MEAK7 MTOR associated protein, eak-7 homolog 2.23428
ZFYVE26 zinc finger, FYVE domain containing 26 2.23327
POLI polymerase (DNA directed) iota 2.22998
PYGB phosphorylase, glycogen; brain 2.22964
GADD45A growth arrest and DNA-damage-inducible, alpha 2.22856
MMP24OS MMP24 opposite strand 2.22632
RAB11A RAB11A, member RAS oncogene family 2.22466
QPCT glutaminyl-peptide cyclotransferase 2.22447
MIDEAS mitotic deacetylase associated SANT domain protein 2.22213
GTPBP2 GTP binding protein 2 2.22204
GRN granulin 2.21598
ANXA3 annexin A3 2.21588
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.21074
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.20894
AUP1 ancient ubiquitous protein 1 2.20885
DSE dermatan sulfate epimerase 2.20856
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 2.20754
BAZ1A bromodomain adjacent to zinc finger domain, 1A 2.20202
PTBP2 polypyrimidine tract binding protein 2 2.2016
TMEM53 transmembrane protein 53 2.19745
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2.19662
DOHH deoxyhypusine hydroxylase/monooxygenase 2.19416
SMAD3 SMAD family member 3 2.19407
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.18751
EFL1 elongation factor like GTPase 1 2.18237
MYL12B myosin, light chain 12B, regulatory 2.18207
OSBPL2 oxysterol binding protein-like 2 2.18056
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.17969
HSPB1 heat shock 27kDa protein 1 2.17591
ERCC1 excision repair cross-complementation group 1 2.17576
MTX1 metaxin 1 2.17492
CLK3 CDC-like kinase 3 2.17465
NSFL1C NSFL1 (p97) cofactor (p47) 2.17197
KCTD17 potassium channel tetramerization domain containing 17 2.16837
MSI1 musashi RNA-binding protein 1 2.16789
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.16778
ZYX zyxin 2.16709
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 2.16688
RTN4 reticulon 4 2.16606
DYNLT3 dynein, light chain, Tctex-type 3 2.16505
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 2.16461
LOC127933115 uncharacterized LOC127933115 2.15846
PLAUR plasminogen activator, urokinase receptor 2.15683
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.15214
ITGAV integrin, alpha V 2.15093
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 2.15067
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.15
ZBTB17 zinc finger and BTB domain containing 17 2.14882
CHMP5 charged multivesicular body protein 5 2.14736
LIG4 ligase IV, DNA, ATP-dependent 2.14605
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 2.14593
ACVR1 activin A receptor, type I 2.1434
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 2.14212
CTTN cortactin 2.1407
PDCD1LG2 programmed cell death 1 ligand 2 2.1406
H2BC4 H2B clustered histone 4 2.13917
RAB3B RAB3B, member RAS oncogene family 2.13405
NAGK N-acetylglucosamine kinase 2.13236
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.12918
ARMCX1 armadillo repeat containing, X-linked 1 2.12657
ZDHHC7 zinc finger, DHHC-type containing 7 2.12357
FILIP1L filamin A interacting protein 1-like 2.12134
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.11553
TUFT1 tuftelin 1 2.11222
RAP1GAP2 RAP1 GTPase activating protein 2 2.11216
RNF25 ring finger protein 25 2.11068
LY96 lymphocyte antigen 96 2.11014
STN1 STN1 subunit of CST complex 2.10738
STEAP1B STEAP family member 1B 2.10562
WSB2 WD repeat and SOCS box containing 2 2.10039
EFHC1 EF-hand domain (C-terminal) containing 1 2.09961
TGIF1 TGFB-induced factor homeobox 1 2.09915
WLS wntless Wnt ligand secretion mediator 2.09815
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.09785
ESYT1 extended synaptotagmin-like protein 1 2.09492
SDF2 stromal cell-derived factor 2 2.09053
TTLL7 tubulin tyrosine ligase-like family member 7 2.09043
KRT19 keratin 19, type I 2.08786
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 2.08784
JUP junction plakoglobin 2.08696
DAD1 defender against cell death 1 2.08222
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 2.07893
FES FES proto-oncogene, tyrosine kinase 2.07846
NDRG4 NDRG family member 4 2.07694
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.07677
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.07668
GULP1 GULP, engulfment adaptor PTB domain containing 1 2.07495
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.07384
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 2.06878
STX4 syntaxin 4 2.06828
PFKP phosphofructokinase, platelet 2.06585
BIRC7 baculoviral IAP repeat containing 7 2.06422
OSBPL1A oxysterol binding protein-like 1A 2.06339
NCF2 neutrophil cytosolic factor 2 2.05998
SPATA7 spermatogenesis associated 7 2.05893
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 2.05074
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.04778
RTF2 replication termination factor 2 2.04582
ABI1 abl-interactor 1 2.04565
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.04484
TMEM134 transmembrane protein 134 2.04478
TOX3 TOX high mobility group box family member 3 2.04315
JUN jun proto-oncogene 2.04164
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 2.04039
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 2.03572
COTL1 coactosin-like F-actin binding protein 1 2.03414
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 2.03376
EFNB2 ephrin-B2 2.03144
VCL vinculin 2.03142
CLDN4 claudin 4 2.03035
KDM6B lysine (K)-specific demethylase 6B 2.02667
NBEAL2 neurobeachin-like 2 2.02659
EIF3D eukaryotic translation initiation factor 3, subunit D 2.02613
SQOR sulfide quinone oxidoreductase 2.02119
GAK cyclin G associated kinase 2.0206
MNT MAX network transcriptional repressor 2.01668
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.0164
TLR4 toll-like receptor 4 2.01463
H1-2 H1.2 linker histone, cluster member 2.01348
MGST3 microsomal glutathione S-transferase 3 2.013
APMAP adipocyte plasma membrane associated protein 2.01284
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.0083
ZNF165 zinc finger protein 165 2.00468
PLK2 polo-like kinase 2 2.00468
HSPA1B heat shock 70kDa protein 1B 2.00409
CTSL cathepsin L 2.00008

decreased expression

Symbol Name Standardized Value
APOA2 apolipoprotein A-II -7.35544
APOH apolipoprotein H (beta-2-glycoprotein I) -7.16381
ASF1B anti-silencing function 1B histone chaperone -7.08278
TOP2A topoisomerase (DNA) II alpha 170kDa -6.82758
BIRC5 baculoviral IAP repeat containing 5 -6.60727
MCM3 minichromosome maintenance complex component 3 -6.57581
PLK1 polo-like kinase 1 -6.49673
NEIL3 nei endonuclease VIII-like 3 (E. coli) -6.41763
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -6.1499
CCNA2 cyclin A2 -6.06926
KIF14 kinesin family member 14 -5.99287
UBE2C ubiquitin-conjugating enzyme E2C -5.86638
CDK1 cyclin-dependent kinase 1 -5.82156
CCNB2 cyclin B2 -5.82001
TROAP trophinin associated protein -5.80149
CDT1 chromatin licensing and DNA replication factor 1 -5.76178
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -5.732
CDC45 cell division cycle 45 -5.70199
HADH hydroxyacyl-CoA dehydrogenase -5.53622
MCM10 minichromosome maintenance complex component 10 -5.39104
CENPE centromere protein E, 312kDa -5.385
OIP5 Opa interacting protein 5 -5.32662
KIF15 kinesin family member 15 -5.30139
BRCA1 breast cancer 1, early onset -5.26679
KIF4A kinesin family member 4A -5.19002
RACGAP1 Rac GTPase activating protein 1 -5.15418
DHFR dihydrofolate reductase -5.14547
PECR peroxisomal trans-2-enoyl-CoA reductase -5.13262
CDC6 cell division cycle 6 -5.11862
HJURP Holliday junction recognition protein -5.08178
MKI67 marker of proliferation Ki-67 -5.03425
RFC3 replication factor C (activator 1) 3, 38kDa -5.00065
SPAG5 sperm associated antigen 5 -4.97314
CDC20 cell division cycle 20 -4.96606
PGM1 phosphoglucomutase 1 -4.91194
FEN1 flap structure-specific endonuclease 1 -4.90107
KIF11 kinesin family member 11 -4.89905
SPC25 SPC25, NDC80 kinetochore complex component -4.88169
MIS18A MIS18 kinetochore protein A -4.87049
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -4.85077
TPX2 TPX2, microtubule-associated -4.77487
KIF18B kinesin family member 18B -4.7734
CENPA centromere protein A -4.71666
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.63279
ATAD2 ATPase family, AAA domain containing 2 -4.63082
FOXM1 forkhead box M1 -4.62512
EXO1 exonuclease 1 -4.60367
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -4.58658
C5 complement component 5 -4.53784
MCM6 minichromosome maintenance complex component 6 -4.52842
HMMR hyaluronan-mediated motility receptor (RHAMM) -4.48783
TRMT5 tRNA methyltransferase 5 -4.47283
CDCA3 cell division cycle associated 3 -4.47058
MCM5 minichromosome maintenance complex component 5 -4.45028
HSPD1 heat shock 60kDa protein 1 (chaperonin) -4.44556
NCAPH non-SMC condensin I complex, subunit H -4.43803
CDC25C cell division cycle 25C -4.42449
TF transferrin -4.39389
KIF20A kinesin family member 20A -4.38663
CHAF1A chromatin assembly factor 1, subunit A (p150) -4.37022
TMEM97 transmembrane protein 97 -4.36867
NEK2 NIMA-related kinase 2 -4.36093
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -4.3272
HELLS helicase, lymphoid-specific -4.31957
TTK TTK protein kinase -4.3126
B4GAT1 beta-1,4-glucuronyltransferase 1 -4.30308
FANCI Fanconi anemia, complementation group I -4.30159
NCAPG2 non-SMC condensin II complex, subunit G2 -4.27183
TRIP13 thyroid hormone receptor interactor 13 -4.26172
POLK polymerase (DNA directed) kappa -4.24744
HMGN2 high mobility group nucleosomal binding domain 2 -4.22366
C3 complement component 3 -4.221
HMGB2 high mobility group box 2 -4.1686
NUSAP1 nucleolar and spindle associated protein 1 -4.15694
DONSON downstream neighbor of SON -4.13041
CDK2 cyclin-dependent kinase 2 -4.12497
PSRC1 proline/serine-rich coiled-coil 1 -4.12375
FANCG Fanconi anemia, complementation group G -4.1221
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -4.10447
VDAC1 voltage-dependent anion channel 1 -4.07353
FANCC Fanconi anemia, complementation group C -4.0694
KIF18A kinesin family member 18A -4.05648
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -4.04443
GINS2 GINS complex subunit 2 (Psf2 homolog) -4.03157
MAT1A methionine adenosyltransferase I, alpha -4.02837
KIFC1 kinesin family member C1 -4.00991
TK1 thymidine kinase 1, soluble -3.99441
A1CF APOBEC1 complementation factor -3.97944
SKA1 spindle and kinetochore associated complex subunit 1 -3.97892
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.96702
ZWINT ZW10 interacting kinetochore protein -3.95402
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.89032
DNA2 DNA replication helicase/nuclease 2 -3.88971
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.8544
ERCC6L excision repair cross-complementation group 6-like -3.84925
ADI1 acireductone dioxygenase 1 -3.83493
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.82925
PAH phenylalanine hydroxylase -3.82585
CDCA8 cell division cycle associated 8 -3.82012
DBF4 DBF4 zinc finger -3.81307
CASP8AP2 caspase 8 associated protein 2 -3.79272
GTSE1 G-2 and S-phase expressed 1 -3.78735
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.78407
SHMT1 serine hydroxymethyltransferase 1 (soluble) -3.77819
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -3.77379
USP1 ubiquitin specific peptidase 1 -3.75927
APOM apolipoprotein M -3.75574
RRM2 ribonucleotide reductase M2 -3.74165
PLK4 polo-like kinase 4 -3.73989
MCM4 minichromosome maintenance complex component 4 -3.72888
POLR1A polymerase (RNA) I polypeptide A, 194kDa -3.72773
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.71629
FBF1 Fas (TNFRSF6) binding factor 1 -3.71253
PYGL phosphorylase, glycogen, liver -3.68142
TEDC2 tubulin epsilon and delta complex 2 -3.66705
CHAF1B chromatin assembly factor 1, subunit B (p60) -3.66662
ATAD5 ATPase family, AAA domain containing 5 -3.64603
ADH6 alcohol dehydrogenase 6 (class V) -3.64575
CEP57 centrosomal protein 57kDa -3.59149
PHGDH phosphoglycerate dehydrogenase -3.59101
LMNB1 lamin B1 -3.57688
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -3.57649
NUP85 nucleoporin 85kDa -3.57598
BORA bora, aurora kinase A activator -3.57371
CCNB1 cyclin B1 -3.57138
PARP1 poly (ADP-ribose) polymerase 1 -3.56879
SLC2A4RG SLC2A4 regulator -3.55702
MSH2 mutS homolog 2 -3.55399
WDR76 WD repeat domain 76 -3.50173
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.49511
RFC2 replication factor C (activator 1) 2, 40kDa -3.48629
NCAPD3 non-SMC condensin II complex, subunit D3 -3.48563
PRC1 protein regulator of cytokinesis 1 -3.48465
UXT ubiquitously-expressed, prefoldin-like chaperone -3.48407
SLC30A10 solute carrier family 30, member 10 -3.48278
APOC3 apolipoprotein C-III -3.46691
PBK PDZ binding kinase -3.44025
NCAPD2 non-SMC condensin I complex, subunit D2 -3.43986
KIF23 kinesin family member 23 -3.43916
NDC80 NDC80 kinetochore complex component -3.43741
MTTP microsomal triglyceride transfer protein -3.43503
CPB2 carboxypeptidase B2 (plasma) -3.42724
DUT deoxyuridine triphosphatase -3.42521
DEPDC1 DEP domain containing 1 -3.41799
MSH6 mutS homolog 6 -3.37524
GGCT gamma-glutamylcyclotransferase -3.37505
CCNF cyclin F -3.35575
TMPO thymopoietin -3.34785
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -3.33621
RAB4A RAB4A, member RAS oncogene family -3.32902
UNG uracil-DNA glycosylase -3.31977
RRM1 ribonucleotide reductase M1 -3.30734
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -3.30214
RFWD3 ring finger and WD repeat domain 3 -3.28448
BARD1 BRCA1 associated RING domain 1 -3.28404
CKAP2 cytoskeleton associated protein 2 -3.28189
KLHDC2 kelch domain containing 2 -3.27189
MCM7 minichromosome maintenance complex component 7 -3.26541
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -3.26254
S100B S100 calcium binding protein B -3.25509
PTTG1 pituitary tumor-transforming 1 -3.2504
CCL16 chemokine (C-C motif) ligand 16 -3.24774
CBX5 chromobox homolog 5 -3.21528
SLC17A2 solute carrier family 17, member 2 -3.20717
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -3.20314
CENPI centromere protein I -3.19951
FBXO5 F-box protein 5 -3.17227
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -3.1669
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.16662
HAT1 histone acetyltransferase 1 -3.16527
MPHOSPH9 M-phase phosphoprotein 9 -3.15355
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -3.15094
AUNIP aurora kinase A and ninein interacting protein -3.14794
BLMH bleomycin hydrolase -3.14198
DMAC2L distal membrane arm assembly component 2 like -3.13312
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -3.13109
GPHN gephyrin -3.1194
PSIP1 PC4 and SFRS1 interacting protein 1 -3.11772
H2AZ2 H2A.Z variant histone 2 -3.11011
LBR lamin B receptor -3.10736
SHCBP1 SHC SH2-domain binding protein 1 -3.09666
HSDL2 hydroxysteroid dehydrogenase like 2 -3.0896
GSTCD glutathione S-transferase, C-terminal domain containing -3.08443
KIF22 kinesin family member 22 -3.08136
AGXT alanine-glyoxylate aminotransferase -3.07757
NUP210 nucleoporin 210kDa -3.07415
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -3.06873
SESN1 sestrin 1 -3.06576
CDC25A cell division cycle 25A -3.05547
SOAT2 sterol O-acyltransferase 2 -3.05318
E2F8 E2F transcription factor 8 -3.05055
ARHGAP11A Rho GTPase activating protein 11A -3.04846
ISOC1 isochorismatase domain containing 1 -3.04611
DSCC1 DNA replication and sister chromatid cohesion 1 -3.04222
DSN1 DSN1, MIS12 kinetochore complex component -3.03741
THOP1 thimet oligopeptidase 1 -3.03616
NEMP1 nuclear envelope integral membrane protein 1 -3.03343
AMBP alpha-1-microglobulin/bikunin precursor -3.03216
CDKN3 cyclin-dependent kinase inhibitor 3 -3.02429
RAD51AP1 RAD51 associated protein 1 -3.01907
ORC6 origin recognition complex, subunit 6 -3.01755
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.01585
MBL2 mannose-binding lectin (protein C) 2, soluble -3.01524
PCLAF PCNA clamp associated factor -2.99265
E2F1 E2F transcription factor 1 -2.98914
INCENP inner centromere protein antigens 135/155kDa -2.98594
SNRPA small nuclear ribonucleoprotein polypeptide A -2.98573
PARPBP PARP1 binding protein -2.98266
CEP55 centrosomal protein 55kDa -2.9789
KYAT1 kynurenine aminotransferase 1 -2.97132
MYO19 myosin XIX -2.97097
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.96823
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -2.96636
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.96615
KIF20B kinesin family member 20B -2.95605
SMC4 structural maintenance of chromosomes 4 -2.9549
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.95205
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.94731
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.94602
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.94397
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -2.94294
CDC23 cell division cycle 23 -2.93655
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.93373
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.92865
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.92716
GINS4 GINS complex subunit 4 (Sld5 homolog) -2.92108
EML4 echinoderm microtubule associated protein like 4 -2.91612
RAD54L RAD54-like (S. cerevisiae) -2.91488
FKTN fukutin -2.91242
PROM1 prominin 1 -2.91135
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.90743
AGMAT agmatine ureohydrolase (agmatinase) -2.90294
CDC25B cell division cycle 25B -2.90159
RFXAP regulatory factor X-associated protein -2.89899
NASP nuclear autoantigenic sperm protein (histone-binding) -2.89761
ANAPC1 anaphase promoting complex subunit 1 -2.89086
MCMBP minichromosome maintenance complex binding protein -2.88903
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -2.8863
GAS2 growth arrest-specific 2 -2.87712
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.87644
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.86895
RBMX RNA binding motif protein, X-linked -2.86663
AHSG alpha-2-HS-glycoprotein -2.86036
CENPU centromere protein U -2.85715
CERS1 ceramide synthase 1 -2.8556
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.85518
MBNL3 muscleblind-like splicing regulator 3 -2.85257
CA5A carbonic anhydrase VA, mitochondrial -2.84184
RBL1 retinoblastoma-like 1 -2.83967
SPDL1 spindle apparatus coiled-coil protein 1 -2.83965
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.8392
MELK maternal embryonic leucine zipper kinase -2.83735
S100PBP S100P binding protein -2.83591
SUZ12 SUZ12 polycomb repressive complex 2 subunit -2.83402
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.82955
APOA1 apolipoprotein A-I -2.82811
FTCD formimidoyltransferase cyclodeaminase -2.8242
CNTLN centlein, centrosomal protein -2.82053
PLP1 proteolipid protein 1 -2.8177
C8A complement component 8, alpha polypeptide -2.81604
AURKB aurora kinase B -2.81206
PIPOX pipecolic acid oxidase -2.80974
CENPM centromere protein M -2.80474
PRUNE1 prune exopolyphosphatase 1 -2.78488
NT5DC2 5'-nucleotidase domain containing 2 -2.77996
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.77318
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.76975
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.76686
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -2.76495
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.76067
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.75851
NUCB2 nucleobindin 2 -2.75479
PRDX5 peroxiredoxin 5 -2.75035
KNG1 kininogen 1 -2.74947
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -2.74709
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.74399
MOCS2 molybdenum cofactor synthesis 2 -2.74363
CHEK2 checkpoint kinase 2 -2.74171
PMP2 peripheral myelin protein 2 -2.73914
TIMELESS timeless circadian clock -2.73823
CENPF centromere protein F, 350/400kDa -2.73186
TACC3 transforming, acidic coiled-coil containing protein 3 -2.73087
HMGA2 high mobility group AT-hook 2 -2.72916
H2AX H2A.X variant histone -2.72687
HPR haptoglobin-related protein -2.72453
RHBG Rh family, B glycoprotein (gene/pseudogene) -2.72145
ZNF552 zinc finger protein 552 -2.71719
ALAD aminolevulinate dehydratase -2.71343
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.71301
AKR1D1 aldo-keto reductase family 1, member D1 -2.70509
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.70491
KHK ketohexokinase (fructokinase) -2.70225
ANAPC15 anaphase promoting complex subunit 15 -2.69903
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.6939
APLNR apelin receptor -2.69164
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.68911
IPO5 importin 5 -2.68735
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.68735
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.68626
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.6846
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -2.68346
MPC2 mitochondrial pyruvate carrier 2 -2.67167
TOMM70 translocase of outer mitochondrial membrane 70 -2.6642
FGA fibrinogen alpha chain -2.66124
HACL2 2-hydroxyacyl-CoA lyase 2 -2.65965
SKI SKI proto-oncogene -2.65883
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.65877
CFI complement factor I -2.65659
DENND1C DENN/MADD domain containing 1C -2.65295
RIDA reactive intermediate imine deaminase A homolog -2.65227
PSAT1 phosphoserine aminotransferase 1 -2.65045
NSD2 nuclear receptor binding SET domain protein 2 -2.63861
ZWILCH zwilch kinetochore protein -2.63762
ASGR1 asialoglycoprotein receptor 1 -2.63353
ELP4 elongator acetyltransferase complex subunit 4 -2.63319
RXRA retinoid X receptor, alpha -2.63097
TBP TATA box binding protein -2.62921
TCOF1 Treacher Collins-Franceschetti syndrome 1 -2.62876
FABP1 fatty acid binding protein 1, liver -2.62858
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 -2.62735
ZNF318 zinc finger protein 318 -2.62495
CENPN centromere protein N -2.62379
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.62257
DCK deoxycytidine kinase -2.62221
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -2.62155
PURA purine-rich element binding protein A -2.61894
ST20-MTHFS ST20-MTHFS readthrough -2.61885
CEP85 centrosomal protein 85kDa -2.61878
RGN regucalcin -2.61727
UBE4B ubiquitination factor E4B -2.61411
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.61301
BLM Bloom syndrome, RecQ helicase-like -2.60998
STIL SCL/TAL1 interrupting locus -2.60726
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -2.60147
CARD8 caspase recruitment domain family, member 8 -2.60042
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.59542
TFDP1 transcription factor Dp-1 -2.59457
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.58872
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -2.58815
RECQL4 RecQ protein-like 4 -2.58426
ORM2 orosomucoid 2 -2.58084
VRK1 vaccinia related kinase 1 -2.57955
MYCBP MYC binding protein -2.57947
C4BPB complement component 4 binding protein, beta -2.57765
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -2.57645
METTL16 methyltransferase like 16 -2.5723
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.57204
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.5708
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.56945
RAD51 RAD51 recombinase -2.56873
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.56802
TADA2A transcriptional adaptor 2A -2.56326
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -2.5621
SMIM8 small integral membrane protein 8 -2.54984
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -2.54631
SH3D19 SH3 domain containing 19 -2.54623
HEBP1 heme binding protein 1 -2.54592
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.54492
MVD mevalonate (diphospho) decarboxylase -2.54145
F7 coagulation factor VII (serum prothrombin conversion accelerator) -2.539
MXD3 MAX dimerization protein 3 -2.53769
APIP APAF1 interacting protein -2.53425
CLASP2 cytoplasmic linker associated protein 2 -2.52654
ARF1 ADP-ribosylation factor 1 -2.52479
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.52216
FGF1 fibroblast growth factor 1 (acidic) -2.52052
L2HGDH L-2-hydroxyglutarate dehydrogenase -2.51924
STMN1 stathmin 1 -2.51703
CSE1L CSE1 chromosome segregation 1-like (yeast) -2.51473
TEX30 testis expressed 30 -2.5111
PON1 paraoxonase 1 -2.51055
PRKCB protein kinase C, beta -2.50774
ARL5A ADP-ribosylation factor-like 5A -2.50473
CKAP5 cytoskeleton associated protein 5 -2.50217
SETD6 SET domain containing 6 -2.49901
PHTF2 putative homeodomain transcription factor 2 -2.49773
SMC1A structural maintenance of chromosomes 1A -2.49768
SNX5 sorting nexin 5 -2.4966
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -2.49613
MAGT1 magnesium transporter 1 -2.49197
HMGB1 high mobility group box 1 -2.48483
PLAC8 placenta-specific 8 -2.48002
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -2.4771
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 -2.47626
MIS18BP1 MIS18 binding protein 1 -2.4761
AQP4 aquaporin 4 -2.47462
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.47199
RPA3 replication protein A3, 14kDa -2.46896
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.46404
CHURC1-FNTB CHURC1-FNTB readthrough -2.4603
ATF7IP2 activating transcription factor 7 interacting protein 2 -2.45953
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.45488
SRP9 signal recognition particle 9kDa -2.45364
SFXN1 sideroflexin 1 -2.45112
FAM107A family with sequence similarity 107, member A -2.44875
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.44391
TRIM25 tripartite motif containing 25 -2.44103
FAM169A family with sequence similarity 169, member A -2.44078
NUP62 nucleoporin 62kDa -2.43794
METTL8 methyltransferase like 8 -2.43496
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.43307
GJB1 gap junction protein, beta 1, 32kDa -2.43211
CEP43 centrosomal protein 43 -2.42611
EMID1 EMI domain containing 1 -2.42514
CCNT1 cyclin T1 -2.42459
RMI1 RecQ mediated genome instability 1 -2.42387
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.4235
PDZK1 PDZ domain containing 1 -2.42348
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.41994
POLR1G RNA polymerase I subunit G -2.41924
WDR62 WD repeat domain 62 -2.41865
EXOSC8 exosome component 8 -2.41421
CCL20 chemokine (C-C motif) ligand 20 -2.41346
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.41196
CRYL1 crystallin, lambda 1 -2.40829
GRID1 glutamate receptor, ionotropic, delta 1 -2.40358
SPOUT1 SPOUT domain containing methyltransferase 1 -2.40242
QSER1 glutamine and serine rich 1 -2.40129
CPAP centrosome assembly and centriole elongation protein -2.40072
TBC1D12 TBC1 domain family, member 12 -2.40065
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.39047
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -2.38411
PM20D1 peptidase M20 domain containing 1 -2.38161
SCN1A sodium channel, voltage gated, type I alpha subunit -2.38075
TMEM267 transmembrane protein 267 -2.37771
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.37709
APOB apolipoprotein B -2.376
PRMT1 protein arginine methyltransferase 1 -2.37241
NPY neuropeptide Y -2.37133
UBAC1 UBA domain containing 1 -2.37005
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 -2.36929
SCARA3 scavenger receptor class A, member 3 -2.3685
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.36614
FBXO31 F-box protein 31 -2.36607
LIME1 Lck interacting transmembrane adaptor 1 -2.36077
ATL2 atlastin GTPase 2 -2.36071
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.35898
RNASEH2B ribonuclease H2, subunit B -2.35865
UPB1 ureidopropionase, beta -2.35835
SCRG1 stimulator of chondrogenesis 1 -2.35731
CDK6 cyclin-dependent kinase 6 -2.35501
GAMT guanidinoacetate N-methyltransferase -2.35489
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -2.34795
XPO7 exportin 7 -2.34523
PLG plasminogen -2.3431
OSBP2 oxysterol binding protein 2 -2.34088
CLDN15 claudin 15 -2.34082
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.3393
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 -2.33674
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.33625
CCDC15 coiled-coil domain containing 15 -2.33064
TTLL4 tubulin tyrosine ligase-like family member 4 -2.33046
DAND5 DAN domain family member 5, BMP antagonist -2.33023
KLF13 Kruppel-like factor 13 -2.33009
COL9A1 collagen, type IX, alpha 1 -2.32899
MSH3 mutS homolog 3 -2.32757
FANCA Fanconi anemia, complementation group A -2.32524
TRIM66 tripartite motif containing 66 -2.32235
HGD homogentisate 1,2-dioxygenase -2.31902
FZD7 frizzled class receptor 7 -2.31901
CES3 carboxylesterase 3 -2.3168
RFX7 regulatory factor X, 7 -2.31634
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) -2.31285
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.3117
MLEC malectin -2.31139
TTF2 transcription termination factor, RNA polymerase II -2.31056
ZBTB24 zinc finger and BTB domain containing 24 -2.31047
CA14 carbonic anhydrase XIV -2.30814
NCKIPSD NCK interacting protein with SH3 domain -2.30478
PCNT pericentrin -2.30444
BRIX1 BRX1, biogenesis of ribosomes -2.3041
NEK4 NIMA-related kinase 4 -2.30221
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -2.3018
SAA4 serum amyloid A4, constitutive -2.29755
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.29556
TUBG1 tubulin, gamma 1 -2.29388
NHEJ1 nonhomologous end-joining factor 1 -2.29214
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.29188
PDS5B PDS5 cohesin associated factor B -2.29108
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -2.28972
STX17 syntaxin 17 -2.28961
MNS1 meiosis-specific nuclear structural 1 -2.28935
NNT nicotinamide nucleotide transhydrogenase -2.28827
MAP3K7 mitogen-activated protein kinase kinase kinase 7 -2.28796
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.2877
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 -2.28701
NUP133 nucleoporin 133kDa -2.2859
HAUS7 HAUS augmin-like complex, subunit 7 -2.28564
NUP37 nucleoporin 37kDa -2.28195
GYG2 glycogenin 2 -2.27782
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -2.27542
RAB33B RAB33B, member RAS oncogene family -2.27517
PSMC3IP PSMC3 interacting protein -2.27335
TPM3 tropomyosin 3 -2.27226
PKNOX1 PBX/knotted 1 homeobox 1 -2.27066
UBA2 ubiquitin-like modifier activating enzyme 2 -2.27052
AKT2 v-akt murine thymoma viral oncogene homolog 2 -2.27027
TDO2 tryptophan 2,3-dioxygenase -2.26923
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.26785
FAM168A family with sequence similarity 168, member A -2.26262
GALK1 galactokinase 1 -2.26081
FMO5 flavin containing monooxygenase 5 -2.25446
SAC3D1 SAC3 domain containing 1 -2.25216
CEP76 centrosomal protein 76kDa -2.25073
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -2.24985
PREB prolactin regulatory element binding -2.2493
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -2.24769
TMEM38B transmembrane protein 38B -2.24119
KRCC1 lysine-rich coiled-coil 1 -2.24082
COPZ1 coatomer protein complex, subunit zeta 1 -2.24075
CD1C CD1c molecule -2.23778
EPHX2 epoxide hydrolase 2, cytoplasmic -2.23656
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.23424
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.23379
OTC ornithine carbamoyltransferase -2.23279
UBE2O ubiquitin-conjugating enzyme E2O -2.2317
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -2.23071
PIMREG PICALM interacting mitotic regulator -2.22897
TIPIN TIMELESS interacting protein -2.22759
LTA lymphotoxin alpha -2.22415
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.22294
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.22201
ELOVL6 ELOVL fatty acid elongase 6 -2.22157
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -2.22125
IPO7 importin 7 -2.22103
EPCIP exosomal polycystin 1 interacting protein -2.21807
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.21203
TRAIP TRAF interacting protein -2.20734
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -2.20724
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -2.20676
TFAM transcription factor A, mitochondrial -2.20446
SEC13 SEC13 homolog (S. cerevisiae) -2.20245
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 -2.20227
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.20149
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.19863
ZNF83 zinc finger protein 83 -2.19827
NANOS2 nanos homolog 2 (Drosophila) -2.19456
ZNF443 zinc finger protein 443 -2.19311
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -2.19249
ASRGL1 asparaginase like 1 -2.19159
SLC25A40 solute carrier family 25, member 40 -2.1867
DHRS11 dehydrogenase/reductase (SDR family) member 11 -2.18602
CEP72 centrosomal protein 72kDa -2.18513
C4BPA complement component 4 binding protein, alpha -2.18372
MPC1 mitochondrial pyruvate carrier 1 -2.18241
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z -2.17761
CCDC88A coiled-coil domain containing 88A -2.17719
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -2.17675
CFHR5 complement factor H-related 5 -2.17594
CD1E CD1e molecule -2.17438
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.17155
FGL1 fibrinogen-like 1 -2.1705
IFRD2 interferon-related developmental regulator 2 -2.16839
LRPPRC leucine-rich pentatricopeptide repeat containing -2.16526
PAAF1 proteasomal ATPase-associated factor 1 -2.16176
DHCR24 24-dehydrocholesterol reductase -2.16067
PCBP2 poly(rC) binding protein 2 -2.1604
CD244 CD244 molecule, natural killer cell receptor 2B4 -2.16036
APOC2 apolipoprotein C-II -2.15409
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.15216
SRSF3 serine/arginine-rich splicing factor 3 -2.14995
ELSPBP1 epididymal sperm binding protein 1 -2.14802
PUS1 pseudouridylate synthase 1 -2.14629
CAPN7 calpain 7 -2.14626
HAUS4 HAUS augmin-like complex, subunit 4 -2.146
TYRO3 TYRO3 protein tyrosine kinase -2.1448
HPX hemopexin -2.14374
CTNND2 catenin (cadherin-associated protein), delta 2 -2.14354
C1S complement component 1, s subcomponent -2.14196
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.14106
TUBD1 tubulin, delta 1 -2.14047
ADD3 adducin 3 (gamma) -2.14037
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 -2.13997
AVPR1B arginine vasopressin receptor 1B -2.13988
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.13983
CHKA choline kinase alpha -2.13734
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.13542
PENK proenkephalin -2.13287
ETNPPL ethanolamine-phosphate phospho-lyase -2.13252
TESK2 testis-specific kinase 2 -2.13191
PPP5C protein phosphatase 5, catalytic subunit -2.1308
AKAP7 A kinase (PRKA) anchor protein 7 -2.13041
FGFR3 fibroblast growth factor receptor 3 -2.12938
CANX calnexin -2.12774
DCPH1 damage control phosphatase 1 -2.12684
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) -2.12505
OSBPL11 oxysterol binding protein-like 11 -2.12441
EDIL3 EGF-like repeats and discoidin I-like domains 3 -2.12437
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.12435
FCHSD2 FCH and double SH3 domains 2 -2.12293
PKLR pyruvate kinase, liver and RBC -2.12173
SLC19A1 solute carrier family 19 (folate transporter), member 1 -2.11775
AHCY adenosylhomocysteinase -2.11689
FKBP3 FK506 binding protein 3, 25kDa -2.11606
HGH1 HGH1 homolog (S. cerevisiae) -2.11577
LCT lactase -2.11445
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -2.11398
PNPLA3 patatin-like phospholipase domain containing 3 -2.11156
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.11124
RPH3A rabphilin 3A -2.10762
GLDC glycine dehydrogenase (decarboxylating) -2.1075
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 -2.10704
SIVA1 SIVA1, apoptosis-inducing factor -2.10702
TRAPPC3 trafficking protein particle complex 3 -2.10606
RPIA ribose 5-phosphate isomerase A -2.1044
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 -2.10417
RBM14-RBM4 RBM14-RBM4 readthrough -2.10381
CHD1L chromodomain helicase DNA binding protein 1-like -2.09997
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.09907
MYF6 myogenic factor 6 (herculin) -2.09804
ACTN2 actinin, alpha 2 -2.09691
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -2.09642
PTCD3 pentatricopeptide repeat domain 3 -2.09626
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G -2.09209
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.09024
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.08884
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -2.08682
SRBD1 S1 RNA binding domain 1 -2.08623
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -2.08575
TMEM106C transmembrane protein 106C -2.08405
C2CD5 C2 calcium-dependent domain containing 5 -2.08314
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.08309
FOXN2 forkhead box N2 -2.08252
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -2.08221
KNTC1 kinetochore associated 1 -2.08124
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -2.08065
TTC13 tetratricopeptide repeat domain 13 -2.07976
TNF tumor necrosis factor -2.07845
TRIM15 tripartite motif containing 15 -2.07554
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.07174
RTRAF RNA transcription, translation and transport factor -2.0675
LIPC lipase, hepatic -2.0657
BAHCC1 BAH domain and coiled-coil containing 1 -2.06538
STRN striatin, calmodulin binding protein -2.06479
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.06419
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -2.05971
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -2.05891
HPD 4-hydroxyphenylpyruvate dioxygenase -2.05691
PRODH2 proline dehydrogenase (oxidase) 2 -2.05464
TMT1A thiol methyltransferase 1A -2.05372
NCOA3 nuclear receptor coactivator 3 -2.05347
PA2G4 proliferation-associated 2G4, 38kDa -2.05325
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.05201
BCAT1 branched chain amino-acid transaminase 1, cytosolic -2.05175
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -2.05062
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.04771
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.04462
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -2.04358
DCAF11 DDB1 and CUL4 associated factor 11 -2.0412
NRF1 nuclear respiratory factor 1 -2.04035
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.03889
ELAVL1 ELAV like RNA binding protein 1 -2.03768
FBLN5 fibulin 5 -2.03714
DPF3 D4, zinc and double PHD fingers, family 3 -2.0368
AK4 adenylate kinase 4 -2.03555
RNFT2 ring finger protein, transmembrane 2 -2.03527
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.03484
TTR transthyretin -2.03469
COASY CoA synthase -2.03297
ORM1 orosomucoid 1 -2.03255
DCAF7 DDB1 and CUL4 associated factor 7 -2.03223
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.03037
TCTN2 tectonic family member 2 -2.03016
NEO1 neogenin 1 -2.02871
CCDC85C coiled-coil domain containing 85C -2.02846
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -2.02805
PLPBP pyridoxal phosphate binding protein -2.02741
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.02703
FN3KRP fructosamine 3 kinase related protein -2.02577
FXYD1 FXYD domain containing ion transport regulator 1 -2.02449
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -2.02431
MRPL16 mitochondrial ribosomal protein L16 -2.02329
DMBT1 deleted in malignant brain tumors 1 -2.02138
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.02098
SORD sorbitol dehydrogenase -2.01898
TMEM209 transmembrane protein 209 -2.01768
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -2.01733
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.01403
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.01326
ZNF551 zinc finger protein 551 -2.01283
DUSP9 dual specificity phosphatase 9 -2.01227
RFC4 replication factor C (activator 1) 4, 37kDa -2.01003
DHCR7 7-dehydrocholesterol reductase -2.00997
ERC1 ELKS/RAB6-interacting/CAST family member 1 -2.00813
TMEM260 transmembrane protein 260 -2.00541
GPT glutamic-pyruvate transaminase (alanine aminotransferase) -2.00485
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.00097