CRCGN015_HEPG2_48H:K01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dichlorophenol 99.3 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_HEPG2_48H:K01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DENND2D DENN/MADD domain containing 2D 3.24193
ANO10 anoctamin 10 2.99063
ADGRE5 adhesion G protein-coupled receptor E5 2.76585
AP2M1 adaptor-related protein complex 2, mu 1 subunit 2.22314
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.20349
GADD45B growth arrest and DNA-damage-inducible, beta 2.14408
TBPL1 TBP-like 1 2.07736

decreased expression

Symbol Name Standardized Value
GOLT1B golgi transport 1B -3.67234
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.34875
PROM1 prominin 1 -3.27368
HAT1 histone acetyltransferase 1 -3.10798
FAIM Fas apoptotic inhibitory molecule -3.03461
RECQL RecQ helicase-like -2.88929
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.45143
ACVR1 activin A receptor, type I -2.2928
INTS13 integrator complex subunit 13 -2.24715
MT1X metallothionein 1X -2.13679
ZNF107 zinc finger protein 107 -2.10537
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) -2.07356
SESN1 sestrin 1 -2.0666
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.02599