CRCGN015_HEPG2_48H:K02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dichlorophenol 33.1 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN015_HEPG2_48H:K02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.45685
FCHO1 FCH domain only 1 2.63346
PRKCQ protein kinase C, theta 2.49576
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.43838
SYNE2 spectrin repeat containing, nuclear envelope 2 2.41502

decreased expression

Symbol Name Standardized Value
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.62333
PLIN2 perilipin 2 -3.13334
RAB4A RAB4A, member RAS oncogene family -2.52781
SYNGR3 synaptogyrin 3 -2.3953
NGRN neugrin, neurite outgrowth associated -2.38845
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.29598