CRCGN015_HEPG2_48H:K03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dichlorophenol 11.03 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_HEPG2_48H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 4.26462
EPHB2 EPH receptor B2 3.90263
CXCR4 chemokine (C-X-C motif) receptor 4 3.32167
FPGS folylpolyglutamate synthase 3.17573
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.78861
TNIP1 TNFAIP3 interacting protein 1 2.53945
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.49831
PZP pregnancy-zone protein 2.04761

decreased expression

Symbol Name Standardized Value
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.93882
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.8995
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.19538
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.04025
SLC35F2 solute carrier family 35, member F2 -2.95492
HEATR1 HEAT repeat containing 1 -2.947
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.92927
CXADR coxsackie virus and adenovirus receptor -2.62192
PDLIM1 PDZ and LIM domain 1 -2.61826
CDC42SE1 CDC42 small effector 1 -2.47188
EIF3G eukaryotic translation initiation factor 3, subunit G -2.1281
APOH apolipoprotein H (beta-2-glycoprotein I) -2.07361