CRCGN015_HEPG2_48H:K06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethoxane 10.98 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN015_HEPG2_48H:K06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CYB561 cytochrome b561 3.69834
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 3.24918
MELK maternal embryonic leucine zipper kinase 2.1401

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.41114
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -4.06457
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.7262
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.39076
CPNE3 copine III -2.93162
TM9SF3 transmembrane 9 superfamily member 3 -2.45993
HSPB1 heat shock 27kDa protein 1 -2.33644
ZBTB35 zinc finger and BTB domain containing 35 -2.0994